BIP! Finder - Dietary Fish Oil Alters DNA Methylation of Genes Involved in Polyunsaturated Fatty Acid Biosynthesis in Muscle and Liver of Atlantic Salmon (Salmo salar)

2019 • Dietary Fish Oil Alters DNA Methylation of Genes Involved in Polyunsaturated Fatty Acid Biosynthesis in Muscle and Liver of Atlantic Salmon (Salmo salar)

Authors: Nicola A. Irvine, Bente Ruyter, Tone-Kari K Østbye, Anna K Sonesson, Karen A. Lillycrop, Gerd Marit Berge, Graham C. Burdge

Venue: Lipids

Type: Publication

Abstract: AbstractAdequate dietary supply of eicosapentaenoic acid (20:5n‐3) and docosahexaenoic acid (22:6n‐3) is required to maintain health and growth of Atlantic salmon (Salmo salar). However, salmon can also convert α‐linolenic acid (18:3n‐3) into eicosapentaenoic acid (20:5n‐3) and docosahexaenoic acid (22:6n‐3) by sequential desaturation and elongation reactions, which can be modified by 20:5n‐3 and 22:6n‐3 intake. In mammals, dietary 20:5n‐3 + 22:6n‐3 intake can modify Fads2 expression (Δ6 desaturase) via altered DNA methyla... (read more)

Topics: Biochemistry

DOI: 10.1002/lipd.12198

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External links: Crossref OpenAIRE

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