Authors: Ignacio Rubio, Marcin F. Osuchowski, Manu Shankar-Hari, Tomasz Skirecki, Martin Sebastian Winkler, Gunnar Lachmann, Paul La Rosée, Guillaume Monneret, Fabienne Venet, Michael Bauer, Frank M. Brunkhorst, Matthijs Kox, Jean-Marc Cavaillon, Florian Uhle, Markus A. Weigand, Stefanie B. Flohé, W. Joost Wiersinga, Marta Martín-Fernández, Raquel Almansa, Ignacio Martin-Loeches, Antoni Torres, Evangelos J. Giamarellos-Bourboulis, Massimo Girardis, Andrea Cossarizza, Mihai G. Netea, Tom van der Poll, André Scherag, Christian Meisel, Joerg C. Schefold, Jesus F. Bermejo-Martin

Venue: The Lancet Infectious Diseases

Type: Publication

Abstract: Increasing evidence supports a central role of the immune system in sepsis, but the current view of how sepsis affects immunity, and vice versa, is still rudimentary. The European Group on Immunology of Sepsis has identified major gaps that should be addressed with high priority, such as understanding how immunological alterations predispose to sepsis, key aspects of the immunopathological events during sepsis, and the long-term consequences of sepsis on patient's immunity. We discuss major unmet topics in those three categories, including the ... (read more)

DOI: 10.7892/boris.134286 (Found 2 versions)