Authors: Anja C, Roden, Julie A, Vrana, Justin W, Koepplin, Angela E, Hudson, Andrew P, Norgan, Garrett, Jenkinson, Satoko, Yamaoka, Hideki, Ebihara, Robert, Monroe, Matthias J, Szabolcs, Ramanath, Majumdar, Ann M, Moyer, Joaquín J, García, Benjamin R, Kipp
Venue: Archives of Pathology & Laboratory Medicine
Type: Publication
Abstract: Context.—Small case series have evaluated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection in formalin-fixed, paraffin-embedded tissue using reverse transcription–polymerase chain reaction, immunohistochemistry (IHC), and/or RNA in situ hybridization (RNAish).Objective.—To compare droplet digital polymerase chain reaction, IHC, and RNAish to detect SARS-CoV-2 in formalin-fixed, paraffin-embedded tissue in a large series of lung specimens from coronavirus disease 2019 (COVID-19) patients.Design.—Droplet digital poly...
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Topics: 
Pathology
Molecular biology
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