BIP! Finder - Targeting Nuclear Receptors with Marine Natural Products

2014 • Targeting Nuclear Receptors with Marine Natural Products

Authors: Yang, Chunyan; Li, Qianrong; Li, Yong

Venue: Marine Drugs

Type: Publication

Abstract: Nuclear receptors (NRs) are important pharmaceutical targets because they are key regulators of many metabolic and inflammatory diseases, including diabetes, dyslipidemia, cirrhosis, and fibrosis. As ligands play a pivotal role in modulating nuclear receptor activity, the discovery of novel ligands for nuclear receptors represents an interesting and promising therapeutic approach. The search for novel NR agonists and antagonists with enhanced selectivities prompted the exploration of the extraordinary chemical diversity associated with natural ... (read more)

Impact:

1.1841799E-8 3.2139986E-9 20 6

/ Attention: 0 20

Topics: Computational biology Bioinformatics

DOI: 10.3390/md12020601

External links: Crossref OpenAIRE

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