BIP! Finder - Subtilomycin: A New Lantibiotic from Bacillus subtilis Strain MMA7 Isolated from the Marine Sponge Haliclona simulans

2013 • Subtilomycin: A New Lantibiotic from Bacillus subtilis Strain MMA7 Isolated from the Marine Sponge Haliclona simulans

Authors: Robert Phelan; Matthieu Barret; Paul Cotter; Paula O'Connor; Rui Chen; John Morrissey; Alan Dobson; Fergal O'Gara; Teresa Barbosa

Venue: Marine Drugs

Type: Publication

Abstract: Bacteriocins are attracting increased attention as an alternative to classic antibiotics in the fight against infectious disease and multidrug resistant pathogens. Bacillus subtilis strain MMA7 isolated from the marine sponge Haliclona simulans displays a broad spectrum antimicrobial activity, which includes Gram-positive and Gram-negative pathogens, as well as several pathogenic Candida species. This activity is in part associated with a newly identified lantibiotic, herein named as subtilomycin. The proposed biosynthetic cluster is composed o... (read more)

Impact:

3.237154E-8 4.5926742E-9 77 23

/ Attention: 0 34

Topics: Microbiology

DOI: 10.3390/md11061878

External links: Crossref OpenAIRE

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