BIP! Finder - PCSK9 Inhibitor causes a decrease in the level of oxidatively modified low-density lipoproteins in patients with coronary artery diseases

2018 • PCSK9 Inhibitor causes a decrease in the level of oxidatively modified low-density lipoproteins in patients with coronary artery diseases

Authors: V Z Lankin, A K Tikhaze, M Viigimaa, I E Chazova

Venue: Terapevticheskii arkhiv

Type: Article

Abstract: Aim. We study the dynamics of oxidatively modified low-density lipoprotein (ox-LDL) content in blood plasma, as well as changes in the activity of key antioxidant enzymes such as Se-containing glutathione peroxidase (GSH-Px) Cu,Zn-superoxide dismutase (SOD) and catalase in erythrocytes of patients with coronary artery disease during treatment with PCSK9 inhibitor (ewolocumab). Materials and methods. The study included 9 men (59 ± 10 years) with coronary artery disease with atherosclerotic lesion at least one main coronary artery according to c... (read more)

Topics: Internal medicine Pharmacology Endocrinology

DOI: 10.26442/terarkh201890927-30

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External links: Crossref , OpenAIRE

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