BIP! Finder - Biological effects induced by Gadolinium nanoparticles on Lymphocyte A20 cell line

2017 • Biological effects induced by Gadolinium nanoparticles on Lymphocyte A20 cell line

Authors: Sorina Nicoleta Voicu; Françoise Chuburu; G Rigaux; Anca Dinischiotu; Maité Callewaert; Cecilia Virginia Gheran

Venue: The EuroBiotech Journal

Type: Publication

Abstract: Abstract Gadolinium nanoparticles (GdNPs) are potential agents for MRI of lymph nodes. The aim of this study was to evaluate the in vitro effects of 1 μM, 2.5 μM and 5 μM of GdDOTA⊂CS-TPP/HA and GdDOTP⊂CS-TPP/HA NPs on A20 lymphocyte cells exposed for 6 and 24 hours. The total cellular biomass (SRB), lactate dehydrogenase activity (LDH) and oxidative stress parameters, such as reactive oxygen species generation (ROS), reduced glutathione (GSH), malondialdehyde (MDA) and advanced oxidation protein products (AOPP) were analyzed by spectrop... (read more)

Impact:

4.8757944E-9 2.7753844E-9 5 1

/ Attention: 0 26

Topics: Biochemistry Molecular biology

DOI: 10.24190/issn2564-615x/2017/01.09

External links: Crossref OpenAIRE

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