BIP! Finder - The Alleviating Effect of Herniarin Against Ionizing Radiation-Induced Genotoxicity and Cytotoxicity in Human Peripheral Blood Lymphocytes

2022 • The Alleviating Effect of Herniarin Against Ionizing Radiation-Induced Genotoxicity and Cytotoxicity in Human Peripheral Blood Lymphocytes

Authors: Mikaeil Molazadeh; Elham Al Fares; Tamar Sanikidze; Sophio Kalmakhelidze; David Topuria; Luigi Mansi; Sean Kitson

Venue: Current Radiopharmaceuticals

Type: Publication

Abstract: Background and Objective: Herniarin is a simple coumarin that is found naturally in some plant species. In this study, we aimed to evaluate the protective effect of herniarin against ionizing radiation-induced genotoxicity and cytotoxicity in human peripheral blood lymphocytes. Methods: Herniarin was added to human lymphocytes before irradiation with a dose of 2 Gy of Xrays. The antagonistic potential of herniarin against radiation was measured by MTT [3-(4,5- dimethyl-2-thiazolyl)-2,5-diphenyl-2H tetrazolium bromide] assay, micronucleus assay,... (read more)

Impact:

4.299423E-9 2.8345986E-9 2 2

/ Attention: 0 22

Topics: Molecular biology Pharmacology Toxicology

DOI: 10.2174/1874471014666211012104808

External links: Crossref OpenAIRE

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