BIP! Finder - The Alleviating Effect Of Herniarin Against Ionizing Radiation-induced Genotoxicity And Cytotoxicity In Human Peripheral Blood Lymphocytes.

2021 • The Alleviating Effect Of Herniarin Against Ionizing Radiation-induced Genotoxicity And Cytotoxicity In Human Peripheral Blood Lymphocytes.

Authors: Elham Al Fares, Tamar Sanikidze, Sophio Kalmakhelidze, David Topuria, Luigi Mansi, Sean Kitson, Mikaeil Molazadeh

Venue: Current Radiopharmaceuticals

Type: Article

Abstract: Herniarin is a simple coumarin that is found naturally insome plant species. In this study, we aimed to evaluate the protective effect of herniarin against ionizingradiation-induced genotoxicity and cytotoxicity in human peripheral blood lymphocytes.Herniarin was added to human lymphocytes before irradiation with a dose of 2 Gy of Xrays.The antagonistic potential of herniarin against radiation was measured by MTT [3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H tetrazolium bromide] assay, micronucleus assay, flow cytometry,and reactive oxygen spec... (read more)

Topics: Molecular biology Pharmacology Toxicology

DOI: 10.2174/1874471014666211012104808

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External links: Crossref , OpenAIRE

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