Abstract: AbstractThe thyroid hormone (TH)–disrupting activity of effluents and environmental water samples in Thailand was surveyed by three in vitro bioassays with different endpoints. These assays test the potency of competitive binding with the active form of TH, 3,3′,5‐[125I]triiodo‐l‐thyronine (T3), to the plasma transport protein transthyretin (TTR) and TH receptor (TR; the TTR assay and TR assay, respectively) and the interference with the cellular T3‐signaling pathway through TR‐mediated luciferase gene activation (the luc assay). ...
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Topics: 
Environmental chemistry