Authors: Robert Pilarski; Sue K. Park; Kyriaki Michailidou; Asta Försti; Ute Hamann; Robert L. Nussbaum; Anthony J. Swerdlow; Antoinette Hollestelle; Maria A. Caligo; Shan Wang-Gohrke; Steve Ellis; Paolo Radice; Mary B. Daly; Montserrat Garcia-Closas; Paolo Peterlongo; Gad Rennert; Siddhartha Kar; Marilie D. Gammon; Carolien H.M. van Deurzen; Jacek Gronwald; Irene Konstantopoulou; Elisabete Weiderpass; Pascal Guénel; Drakoulis Yannoukakos; Peter Kraft; Per Hall; Hermann Brenner; Simona Agata; Matthias W. Beckmann; Daniel F. Schmidt; Hiltrud Brauch; Susan M. Gapstur; Daniel Barrowdale; Esther M. John; Gord Glendon; Elinor J. Sawyer; Volker Arndt; Frans B. L. Hogervorst; Ava Kwong; Nazneen Rahman; Rosa B. Barkardottir; Riccardo Dolcetti; Martine Dumont; Robert Winqvist; Melissa C. Southey; Ramunas Janavicius; Brita Arver; Curtis Olswold; William J. Tapper; W. D. Foulkes; Csilla I. Szabo; Stig E. Bojesen; Fergus J. Couch; Conxi Lázaro; Lothar Haeberle; Cecilia M. Dorfling; David E. Goldgar; Julie M. Cunningham; Christopher A. Haiman; Jan Lubinski; D Thompson; Francesca Damiola; Mary Beth Terry; Jirong Long; Silje Nord; Edith Olah; Nadine Tung; Jenny Chang-Claude; Bernardo Bonanni; Hoda Anton-Culver; Peter A. Fasching; Mia M. Gaudet; Dieter Flesch-Janys; Tara M. Friebel; Anna González-Neira; Janet E. Olson; Eitan Friedman; Angela Cox; Evgeny N. Imyanitov; Barbara Burwinkel; Ana Osorio; Marc J. Gunter; Roger L. Milne; Alvaro A.N. Monteiro; John W. M. Martens; M. Pilar Zamora; Georgia Chenevix-Trench; Diether Lambrechts; Paul D.P. Pharoah; Wei Zheng; Veli-Matti Kosma; Petra H.M. Peeters; Yuan C. Ding; Emiel J. Rutgers; Sue Healey; Natalia Bogdanova; Robert N. Hoover; Stephen J. Chanock; Lars Beckmann; Alfons Meindl; Ian Tomlinson; Trinidad Caldés; Habibul Ahsan; Stephanie V. Blank; Helen Tsimiklis; Emily Hallberg; Karoline Kuchenbaecker; Clare Turnbull; Peter Devilee; Tomasz Huzarski; Børge G. Nordestgaard; Isabel dos-Santos-Silva; Keith Humphreys; Susan L. Slager; Celine M. Vachon; Johanna Rantala; Alex Teulé; Loic Le Marchand; Thomas Hansen; Saundra S. Buys; Marjanka K. Schmidt; Amanda E. Toland; SA Gayther; Katherine L. Nathanson; Sofia Khan; John L. Hopper; Simon S. Cross; Jenny Lester; Leigha Senter; Andrea L. Richardson; Sara Margolin; Antonis C. Antoniou; Enes Makalic; Judy Garber; Rodney J. Scott; Penelope Miron; Susan L. Neuhausen; Manuel R. Teixeira; Isabelle Romieu; Elizabeth J. van Rensburg; Phuong L. Mai; Jianjun Liu; Christine Rappaport; Taru A. Muranen; Carl Blomqvist; Hatef Darabi; Yon Ko; Marike Gabrielson; Song Yao; Alice S. Whittemore; Manjeet K. Bolla; Sylvie Mazoyer; David J. Hunter; Anne-Marie Gerdes; Dominique Stoppa-Lyonnet; Patricia A. Ganz; Beth Y. Karlan; Mark E. Robson; Rita K. Schmutzler; Eunjung Lee; Katri Pylkäs; Steven N. Hart; Hans Wildiers; Debra Frost; Mads Thomassen; Heather Eliassen; Robert A.E.M. Tollenaar; Anna Jakubowska; Laima Tihomirova; Annika Lindblom; Janna Lilyquist; Susan M. Domchek; Miguel de la Hoya; Yael Laitman; Tuomas Heikkinen; Priyanka Sharma; Claudine Isaacs; Kathleen Claes; Rulla M. Tamimi; Maya Ghoussaini; Alison M. Dunning; Bernard Peissel; Florentia Fostira; Muhammad G. Kibriya; Catherine M. Phelan; Frederik Marme; Zhaoming Wang; Penny Soucy; Brian E. Henderson; Anna Marie Mulligan; Austin Miller; Giski Ursin; Julian Peto; Marco Montagna; Soo-Hwang Teo; Rosario Tumino; Bruce Poppe; Banu Arun; Olufunmilayo I. Olopade; Kenneth Offit; Lesley McGuffog; M.J. Hooning; Arto Mannermaa; Christine B. Ambrosone; Kathleen E. Malone; Noralane M. Lindor; Marie Stenmark-Askmalm; María José Sánchez; Andrew K. Godwin; Fredrick R. Schumacher; Wendy K. Chung; Kay-Tee Khaw; Javier Benitez; Paul A. James; Doris Steinemann; Hans Ehrencrona; Xiaohong R. Yang; S. Lindstrom; Raymonda Varon-Mateeva; Graham G. Giles; Julia A. Knight; Uffe Birk Jensen; Jacques Simard; Federico Canzian; Arif B. Ekici; Christian F. Singer; Jeffrey N. Weitzel; Mark S. Goldberg; Michael Jones; Kamila Czene; Irene L. Andrulis; Orland Diez; Jane Carpenter; Siranoush Manoukian; Jonine Figueroa; Maria Kabisch; Anja Rudolph; Mark H. Greene; Olga M. Sinilnikova; Josef Herzog; Regina M. Santella; Monica Barile; Kristiina Aittomäki; Diana Eccles; Thérèse Truong; Gustavo Mendoza-Fandiño; Vessela N. Kristensen; Heli Nevanlinna; Douglas F. Easton

Venue: Nature Communications

Type: Publication

Abstract: AbstractCommon variants in 94 loci have been associated with breast cancer including 15 loci with genome-wide significant associations (P<5 × 10−8) with oestrogen receptor (ER)-negative breast cancer and BRCA1-associated breast cancer risk. In this study, to identify new ER-negative susceptibility loci, we performed a meta-analysis of 11 genome-wide association studies (GWAS) consisting of 4,939 ER-negative cases and 14,352 controls, combined with 7,333 ER-negative cases and 42,468 controls and 15,252 BRCA1 mutation carriers genotyped on ... (read more)

DOI: 10.17863/cam.682