Abstract: Background : Bronchial asthma (BA) is one of the most spreading chronic lung pathology in the world. The disease is characterized by high heterogeneity of clinical phenotypes including resistant forms which provoke significant clinical problem. Immune shift from Th2 to alternative immunological response is considered to be a mechanism of drug-resistance in BA treatment but this issue is not considerably studied yet. Aims : Detection of distinctive patterns in cytokine secretion and genetic expression (ZAP-70, FYN and LAT) of naive and concanava...
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Topics: 
Immunology
Internal medicine