Authors: Helen R. Warren; Dieter Flesch-Janys; Cheng Har Yip; Sara Lindström; Alan Ashworth; Irene Konstantopoulou; Paolo Peterlongo; Sara Margolin; Ching Wan Chan; R.A.E.M. Tollenaar; Jorge L. Rodriguez-Gil; Daehee Kang; Nicholas G. Martin; Hidemi Ito; Jan Lubinski; Laurence N. Kolonel; Kristiina Aittomäki; Elisa V. Bandera; Robert Winqvist; Elisabete Weiderpass; Pascal Guénel; Hermann Brenner; Olivia Fletcher; Gary K. Chen; Montserrat Garcia-Closas; Diether Lambrechts; Artitaya Lophatananon; W. Ryan Diver; Nils Schoof; Daniel Vincent; Elio Riboli; Daniel I. Chasman; Emiel J. Th. Rutgers; Michael P. Lux; Federick Marme; Chia-Ni Hsiung; Katarzyna Durda; Laura Baglietto; Roger L. Milne; Per Hall; Esther M. John; Claudia Rauh; Susan L. Slager; Carl Blomqvist; Douglas F. Easton; Anthony J. Swerdlow; Gianluca Severi; Maartje J. Hooning; Antoinette Hollestelle; Vesa Kataja; Daniel C. Tessier; Kyriaki Michailidou; Stefan Nickels; Hiroji Iwata; Nur Aishah Taib; Guillermo Pita; Gord Glendon; Fernando Rivadeneira; Chiu-Chen Tseng; Rosemary L. Balleine; Pierre Kerbrat; Arja Jukkola-Vuorinen; Ute Hamann; Ian Tomlinson; Stephen J. Chanock; Lars Beckmann; Alfons Meindl; Daniele Campa; Yu Tang Gao; Petra H.M. Peeters; Jenny Chang-Claude; Jonine D. Figueroa; Mieke Kriege; David Van Den Berg; Soo Hwang Teo; Sandra Deming-Halverson; Harsh B. Pathak; Minh Bui; Nazneen Rahman; Mattias Johansson; Foluso O. Ademuyiwa; Patrick Neven; Xianshu Wang; Hanne Meijers-Heijboer; Paolo Radice; Saila Kauppila; Sarah J. Nyante; Christof Sohn; Malcolm W.R. Reed; Annika Lindblom; Clare Turnbull; Elinor J. Sawyer; Jose Ignacio Arias Perez; Daniel F. Schmidt; Walter C. Willett; Volker Arndt; Rosario Tumino; Celine M. Vachon; Hiltrud Brauch; M. Rosario Alonso; Gerhard A. Coetzee; Yon Ko; Hui Cai; Keitaro Matsuo; Henrik Flyger; Pei Ei Wu; Fleur Hammet; Christine D. Berg; Kamila Czene; Irene L. Andrulis; Peter Lichtner; Jane Carpenter; Chen-Yang Shen; Thilo Dörk; Laura J. van't Veer; Robert N. Hoover; Michael G. Schrauder; Fredrick R. Schumacher; Constance Chen; Heather Spencer Feigelson; Thomas Brüning; Hoda Anton-Culver; Julia A. Knight; Jianjun Liu; Ans M.W. van den Ouweland; Ruth C. Travis; Robert M. Millikan; Martha J. Shrubsole; Carolien H.M. van Deurzen; Matthias W. Beckmann; Andrew H. Beck; Jaana M. Hartikainen; Melissa C. Southey; Stig E. Bojesen; Wei Zheng; Sabapathy P. Balasubramanian; Peter Kraft; Curtis Olswold; David J. Hunter; Børge G. Nordestgaard; Loris Bernard; Kirsimari Aaltonen; Loic Le Marchand; Sebastian M. Jud; Wei Lu; Rebecca Hein; Nicola Miller; William J. Tapper; Mark S. Goldberg; Penelope Miron; Sue Gerty; Fergus J. Couch; Christa Stegmaier; Hui Miao; Jolanta Lissowska; Magdalena Lochmann; Regina G. Ziegler; Jacques Simard; Xiao-Ou Shu; Barbara Burwinkel; Rudolf Kaaks; Georgia Chenevix-Trench; Jirong Long; Daniel J. Park; John L. Hopper; Jyh Cherng Yu; Graham G. Giles; Mark N. Brook; Natalia Antonenkova; Susan E. Hankinson; Yasushi Yatabe; William Blot; Michael Jones; Peter Devillee; Dimitrios Trichopoulos; Mark E. Sherman; Manjeet K. Bolla; Robert Pilarski; Astrid Irwanto; Anna Jakubowska; Christina Justenhoven; Marjanka K. Schmidt; Isabel dos Santos Silva; Jennifer J. Hu; Simon S. Cross; Christine B. Ambrosone; Dario Greco; Mitul Shah; Lorraine Durcan; Ching-Yu Cheng; Priyanka Sharma; Francois Bacot; Bernard Peissel; Suhn K. Rhie; Vessela N. Kristensen; Karin Leunen; Joe Dennis; Heli Nevanlinna; Veli-Matti Kosma; Helen Tsimiklis; Diana Eccles; Katarzyna Jaworska; Sarah Stewart-Brown; Thérèse Truong; Arto Mannermaa; Michael F. Press; Quinten Waisfisz; Anna H. Wu; Catriona McLean; Alison M. Dunning; Ye Feng; Annegien Broeks; Caroline M. Seynaeve; Kee Seng Chia; Mia M. Gaudet; Lisa B. Signorello; Michael J. Kerin; Andrew K. Godwin; JoEllen Weaver; Sue A. Ingles; Rita K. Schmutzler; Mikael Hartman; Anna González-Neira; Arif B. Ekici; Ed Dicks; Kay-Tee Khaw; Primitiva Menéndez; André G. Uitterlinden; Enes Makalic; Qin Wang; Nick Orr; Taru A. Muranen; Nichola Johnson; Dennis J. Slamon; Anna Marie Mulligan; Anne Sophie Dieudonne; Heiko Müller; Pornthep Siriwanarangsan; Qiuyin Cai; Peter A. Fasching; Janet E. Olson; Leslie Bernstein; Christopher A. Haiman; Angela Cox; Lorna Gibson; Grant W. Montgomery; Paul D.P. Pharoah; Kenneth Muir; Julian Peto; Bertram Müller-Myhsok; William J. Howat; Françoise Clavel-Chapelon; Julie E. Buring; Andreas Schneeweiss; Tuomas Heikkinen; Pierre Laurent-Puig; Norbert Dahmen; Katri Pylkäs; Jennifer Stone; Martine Dumont; Suleeporn Sangrajrang; Kristen N. Stevens; Brian E. Henderson; Sune F. Nielsen; Anja Rudolph; Javier Benitez; Federico Canzian; Daniel O. Stram; Natalia Bogdanova

Venue: Nature Genetics

Type: Publication

Abstract: Estrogen receptor (ER)-negative tumors represent 20-30% of all breast cancers, with a higher proportion occurring in younger women and women of African ancestry. The etiology and clinical behavior of ER-negative tumors are different from those of tumors expressing ER (ER positive), including differences in genetic predisposition. To identify susceptibility loci specific to ER-negative disease, we combined in a metaanalysis 3 genome-wide association studies of 4,193 ER-negative breast cancer cases and 35,194 controls with a series of 40 follow-u... (read more)

DOI: 10.13025/24710