BIP! Finder - The methylome of Biomphalaria glabrata and other mollusks: enduring modification of epigenetic landscape and phenotypic traits by a new DNA methylation inhibitor

2020 • The methylome of Biomphalaria glabrata and other mollusks: enduring modification of epigenetic landscape and phenotypic traits by a new DNA methylation inhibitor

Authors: Christoph Grunau; Fleur Gawehns; Slavica Ivanovic; Patrice David; Paola B. Arimondo; Koen J. F. Verhoeven; Nelia Luviano; Marie Lopez; Cristian Chaparro; Céline Cosseau

Venue: Epigenetics & Chromatin

Type: Publication

Abstract: Abstract Background 5-Methylcytosine (5mC) is an important epigenetic mark in eukaryotes. Little information about its role exists for invertebrates. To investigate the contribution of 5mC to phenotypic variation in invertebrates, alteration of methylation patterns needs to be produced. Here, we apply new non-nucleoside DNA methyltransferase inhibitors (DNMTi) to introduce aleatory changes into the methylome of mollusk species. Results Flavanone inhibitor Flv1 was efficient in reducing 5mC in the freshwater snails Biomphalaria glabrata and Phys... (read more)

Impact:

1.0614446E-8 3.0630425E-9 9 8

/ Attention: 0 18

Topics: Genetics Evolutionary biology

DOI: 10.1186/s13072-021-00422-7

External links: Crossref OpenAIRE

Related works: Dataset 2

Found 2 versions BibTex PDF

Topic-specific impact indicators

Popularity:
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
Influence:
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
Citation Count:
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
Impulse:
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.