BIP! Finder - Genomic analysis of codon usage shows influence of mutation pressure, natural selection, and host features on Marburg virus evolution

2015 • Genomic analysis of codon usage shows influence of mutation pressure, natural selection, and host features on Marburg virus evolution

Authors: Muhammad Idrees; Yigang Tong; Izza Nasrullah; Shifa Tahir; Azeem Mehmood Butt

Venue: BMC Evolutionary Biology

Type: Publication

Abstract: Abstract Background The Marburg virus (MARV) has a negative-sense single-stranded RNA genome, belongs to the family Filoviridae, and is responsible for several outbreaks of highly fatal hemorrhagic fever. Codon usage patterns of viruses reflect a series of evolutionary changes that enable viruses to shape their survival rates and fitness toward the external environment and, most importantly, their hosts. To understand the evolution of MARV at the codon level, we report a comprehensive analysis of synonymous codon usage patterns in MARV genomes.... (read more)

Impact:

5.5419818E-8 5.8717524E-9 102 23

/ Attention: 0 10

Topics: Genetics Evolutionary biology

DOI: 10.1186/s12862-015-0456-4

External links: Crossref OpenAIRE

Related works: Other 2 Dataset 2

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