BIP! Finder - HIV treatment simplification to elvitegravir/cobicistat/emtricitabine/tenofovir disproxil fumarate (E/C/F/TDF) plus darunavir: a pharmacokinetic study

2017 • HIV treatment simplification to elvitegravir/cobicistat/emtricitabine/tenofovir disproxil fumarate (E/C/F/TDF) plus darunavir: a pharmacokinetic study

Authors: Harris, Marianne; Ganase, Bruce; Watson, Birgit; Harrigan, P. R; Montaner, Julio S G; Hull, Mark W

Venue: AIDS Research and Therapy

Type: Publication

Abstract: Abstract Background As a simplification strategy for treatment-experienced HIV-infected patients who have achieved virologic suppression on a multi-drug, multi-class antiretroviral regimen, the aim of this study was to evaluate the safety, efficacy, and pharmacokinetics of once-daily elvitegravir/cobicistat/emtricitabine/tenofovir disproxil fumarate (E/C/F/TDF) with darunavir. Methods A single arm, open-label 48-week study was conducted of regimen simplification to E/C/F/TDF plus darunavir 800 mg daily from stable therapy including two nucleosi... (read more)

Topics: Internal medicine Pharmacology

DOI: 10.1186/s12981-017-0185-4

BIP! social metrics: 0 12
External links: Crossref OpenAIRE

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