Authors: Zoé L E, van Kempen, Eileen W, Stalman, Maurice, Steenhuis, Laura Y L, Kummer, Koos P J, van Dam, Maarten F, Wilbrink, Anja, Ten Brinke, S Marieke, van Ham, Taco, Kuijpers, Theo, Rispens, Filip, Eftimov, Luuk, Wieske, Joep, Killestein, J, de Wit
Venue: Journal of Neurology, Neurosurgery & Psychiatry
Type: Publication
Abstract: BackgroundIt is unclear which patients with multiple sclerosis (MS) are most susceptible for omicron breakthrough infections.MethodsWe assessed omicron breakthrough infections in vaccinated patients with MS with and without disease-modifying therapies enrolled in an ongoing large prospective study. We longitudinally studied humoral responses after primary and booster vaccinations and breakthrough infections.ResultsOmicron breakthrough infections were reported in 110/312 (36%) patients with MS, and in 105/110 (96%) infections were mild. Omicron ...
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