Authors: Blanca Taboada, Joel Armando Vazquez-Perez, José Esteban Muñoz-Medina, Pilar Ramos-Cervantes, Marina Escalera-Zamudio, Celia Boukadida, Alejandro Sanchez-Flores, Pavel Isa, Edgar Mendieta-Condado, José A. Martínez-Orozco, Eduardo Becerril-Vargas, Jorge Salas-Hernández, Ricardo Grande, Carolina González-Torres, Francisco Javier Gaytán-Cervantes, Gloria Vazquez, Francisco Pulido, Adnan Araiza-Rodríguez, Fabiola Garcés-Ayala, Cesar Raúl González-Bonilla, Concepción Grajales-Muñiz, Víctor Hugo Borja-Aburto, Gisela Barrera-Badillo, Susana López, Lucía Hernández-Rivas, Rogelio Perez-Padilla, Irma López-Martínez, Santiago Ávila-Ríos, Guillermo Ruiz-Palacios, José Ernesto Ramírez-González, Carlos F. Arias

Venue: Journal of Virology

Type: Article

Abstract: Understanding the introduction, spread, and establishment of SARS-CoV-2 within distinct human populations as well as the evolution of the pandemics is crucial to implement effective control strategies. In this work, we report that the initial virus strains introduced in Mexico came from Europe and the United States and that the virus was circulating locally in the country as early as mid-March. We also found evidence for early local transmission of strains with a H49Y mutation in the Spike protein, which could be further used as a molecular mar... (read more)

DOI: 10.1128/jvi.01056-20