Authors: Taboada, Blanca; Vazquez-Perez, Joel Armando; Muñoz-Medina, José Esteban; Ramos-Cervantes, Pilar; Escalera-Zamudio, Marina; Boukadida, Celia; Sanchez-Flores, Alejandro; Isa, Pavel; Mendieta-Condado, Edgar; Martínez-Orozco, José A.; Becerril-Vargas, Eduardo; Salas-Hernández, Jorge; Grande, Ricardo; González-Torres, Carolina; Gaytán-Cervantes, Francisco Javier; Vazquez, Gloria; Pulido, Francisco; Araiza-Rodríguez, Adnan; Garcés-Ayala, Fabiola; González-Bonilla, Cesar Raúl; Grajales-Muñiz, Concepción; Borja-Aburto, Víctor Hugo; Barrera-Badillo, Gisela; López, Susana; Hernández-Rivas, Lucía; Perez-Padilla, Rogelio; López-Martínez, Irma; Ávila-Ríos, Santiago; Ruiz-Palacios, Guillermo; Ramírez-González, José Ernesto; Arias, Carlos F.

Venue: Journal of Virology

Type: Publication

Abstract: Understanding the introduction, spread, and establishment of SARS-CoV-2 within distinct human populations as well as the evolution of the pandemics is crucial to implement effective control strategies. In this work, we report that the initial virus strains introduced in Mexico came from Europe and the United States and that the virus was circulating locally in the country as early as mid-March. We also found evidence for early local transmission of strains with a H49Y mutation in the Spike protein, which could be further used as a molecular mar... (read more)

DOI: 10.1128/jvi.01056-20