BIP! Finder - Moxidectin and Ivermectin Inhibit SARS-CoV-2 Replication in Vero E6 Cells but Not in Human Primary Bronchial Epithelial Cells

2021 • Moxidectin and Ivermectin Inhibit SARS-CoV-2 Replication in Vero E6 Cells but Not in Human Primary Bronchial Epithelial Cells

Authors: Dinesh Kumar, Nilima; ter Ellen, Bram M.; Bouma, Ellen M.; Troost, Berit; van de Pol, Denise P. I.; van der Ende-Metselaar, Heidi H.; van Gosliga, Djoke; Apperloo, Leonie; Carpaij, Orestes A.; van den Berge, Maarten; Nawijn, Martijn C.; Stienstra, Ymkje; Rodenhuis-Zybert, Izabela A.; Smit, Jolanda M.

Venue: Antimicrobial Agents and Chemotherapy

Type: Publication

Abstract: Antiviral therapies are urgently needed to treat and limit the development of severe COVID-19 disease. Ivermectin, a broad-spectrum anti-parasitic agent, has been shown to have anti-SARS-CoV-2 activity in Vero cells at a concentration of 5 μM.

Impact:

1.9838577E-8 3.4281866E-9 18 18

/ Attention: 0 17

Topics: Virology Microbiology Pharmacology

DOI: 10.1128/aac.01543-21

External links: Crossref OpenAIRE

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