Authors: Walid Abuhammour, Lemis Yavuz, Ruchi Jain, Khawla Abu Hammour, Ghalia F. Al-Hammouri, Maha El Naofal, Nour Halabi, Sawsan Yaslam, Sathishkumar Ramaswamy, Alan Taylor, Deena Wafadari, Ali Alsarhan, Hamda Khansaheb, Zulfa Omar Deesi, Rupa Murthy Varghese, Mohammed Uddin, Hanan Al Suwaidi, Abdulmajeed Alkhaja, Laila Mohamed AlDabal, Tom Loney, Norbert Nowotny, Abdulla Al Khayat, Alawi Alsheikh-Ali, Ahmad Abou Tayoun

Venue: Medrxiv

Type: Article

Abstract: Clinical, genetic and laboratory characteristics of patients with multisystem inflammatory syndrome in children (MIS-C) in the Middle East have not yet been documented.To uncover rare genetic variants contributing to MIS-C in patients of primarily Arab and Asian origin.A prospective multicenter cohort study was conducted between September 2020 and August 2021 in the United Arab Emirates and Jordan. Forty-five patients meeting the case definition of MIS-C, and a matched control group of twenty-five healthy children with a confirmed severe acute ... (read more)

DOI: 10.1101/2021.11.30.21267109