BIP! Finder - Hamster and ferret experimental infection with intranasal low dose of a single strain of SARS-CoV-2

2020 • Hamster and ferret experimental infection with intranasal low dose of a single strain of SARS-CoV-2

Authors: Elodie Monchatre-Leroy, Sandrine Lesellier, Marine Wasniewski, Evelyne Picard-Meyer, Céline Richomme, Franck Boué, Sandra Lacôte, Séverine Murri, Coralie Pulido, Johann Vulin, Francisco J Salguero, Meriadeg Ar Gouilh, Alexandre Servat, Philippe Marianneau

Venue: Biorxiv

Type: Article

Abstract: Understanding the pathogenesis of the SARS-CoV-2 infection is key to develop preventive and therapeutic strategies against COVID-19, in the case of severe illness but also when the disease is mild. The use of appropriate experimental animal models remains central in the in-vivo exploration of the physiopathology of infection and antiviral strategies. This study describes SARS-CoV-2 intra-nasal infection in ferrets and hamsters with low doses of low-passage SARS-CoV-2 clinical French isolate UCN19, describing infection levels, excretion, immune ... (read more)

Topics: Virology Immunology

DOI: 10.1101/2020.09.24.311977

BIP! social metrics: 0 1
External links: Crossref , OpenAIRE

References (30) Citations (5) BibTex PDF

Overall Ranking

Ranking within Venue

Impact aspects and other metrics

Popularity: This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
Influence: This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
Citation Count: This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
Impulse: This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.