BIP! Finder - Hamster and ferret experimental infection with intranasal low dose of a single strain of SARS-CoV-2

2020 • Hamster and ferret experimental infection with intranasal low dose of a single strain of SARS-CoV-2

Authors: Elodie Monchatre-Leroy; Sandrine Lesellier; Marine Wasniewski; Evelyne Picard-Meyer; Céline Richomme; Franck Boué; Sandra Lacôte; Séverine Murri; Coralie Pulido; Johann Vulin; Francisco J. Salguero; Meriadeg Ar Gouilh; Alexandre Servat; Philippe Marianneau

Venue: Journal of General Virology

Type: Publication

Abstract: AbstractUnderstanding the pathogenesis of the SARS-CoV-2 infection is key to develop preventive and therapeutic strategies against COVID-19, in the case of severe illness but also when the disease is mild. The use of appropriate experimental animal models remains central in the in-vivo exploration of the physiopathology of infection and antiviral strategies. This study describes SARS-CoV-2 intra-nasal infection in ferrets and hamsters with low doses of low-passage SARS-CoV-2 clinical French isolate UCN19, describing infection levels, excretion,... (read more)

Impact:

4.976703E-8 4.2395687E-9 49 41

/ Attention: 0 18

Topics: Virology Immunology Pathology

DOI: 10.1101/2020.09.24.311977

External links: Crossref OpenAIRE

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