BIP! Finder - Antibody responses to SARS-CoV2 are distinct in children with MIS-C compared to adults with COVID-19

2020 • Antibody responses to SARS-CoV2 are distinct in children with MIS-C compared to adults with COVID-19

Authors: Weisberg, Stuart P.; Connors, Thomas; Zhu, Yun; Baldwin, Matthew; Lin, Wen-hsuan; Wontakal, Sandeep; Szabo, Peter A.; Wells, Steven B.; Dogra, Pranay; Gray, Joshua; Idzikowski, Emma; Bovier, Francesca T.; Davis-Porada, Julia; Matsumoto, Rei; Li Poon, Maya Meimei; Chait, Michael; Mathieu, Cyrille; Horvat, Branka; Decimo, Didier; Bitan, Zachary C.; La Carpia, Francesca; Ferrara, Stephen A.; Mace, Emily; Milner, Joshua; Moscona, Anne; Hod, Eldad; Porotto, Matteo; Farber, Donna L.

Venue: N/A

Type: Publication

Abstract: ABSTRACTClinical manifestations of COVID-19 caused by the novel coronavirus SARS-CoV-2 are associated with age. While children are largely spared from severe respiratory disease, they can present with a SARS-CoV-2-associated multisystem inflammatory syndrome (MIS-C) similar to Kawasaki’s disease. Here, we show distinct antibody (Ab) responses in children with MIS-C compared to adults with severe COVID-19 causing acute respiratory distress syndrome (ARDS), and those who recovered from mild disease. There was a reduced breadth and specificity o... (read more)

Impact:

3.7212473E-8 5.8970584E-9 46 45

/ Attention: 0 38

Topics: Immunology

DOI: 10.1101/2020.07.12.20151068

External links: Crossref OpenAIRE

Related works: Dataset 1

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