BIP! Finder - Machine intelligence design of 2019-nCoV drugs

2020 • Machine intelligence design of 2019-nCoV drugs

Authors: Gao, Kaifu; Nguyen, Duc Duy; Wang, Rui; Wei, Guo-Wei

Venue: N/A

Type: Publication

Abstract: AbstractWuhan coronavirus, called 2019-nCoV, is a newly emerged virus that infected more than 9692 people and leads to more than 213 fatalities by January 30, 2020. Currently, there is no effective treatment for this epidemic. However, the viral protease of a coronavirus is well-known to be essential for its replication and thus is an effective drug target. Fortunately, the sequence identity of the 2019-nCoV protease and that of severe-acute respiratory syndrome virus (SARS-CoV) is as high as 96.1%. We show that the protease inhibitor binding s... (read more)

Impact:

2.8648882E-8 4.6870916E-9 42 42

/ Attention: 0 14

Topics: Virology Pharmacology

DOI: 10.1101/2020.01.30.927889

External links: Crossref OpenAIRE

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