BIP! Finder - Standardization and Harmonization of Distributed Multi-National Proteotype Analysis supporting Precision Medicine Studies

2020 • Standardization and Harmonization of Distributed Multi-National Proteotype Analysis supporting Precision Medicine Studies

Authors: Xuan, Yue; Bateman, Nicholas W.; Gallien, Sebastien; Goetze, Sandra; Zhou, Yue; Navarro, Pedro; Hu, Mo; Parikh, Niyati; Hood, Brian L.; Conrads, Kelly A.; Loosse, Christina; Kitata, Reta Birhanu; Piersma, Sander R.; Chiasserini, Davide; Zhu, Hongwen; Hou, Guixue; Tahir, Muhammad; Macklin, Andrew; Khoo, Amanda; Sun, Xiuxuan; Crossett, Ben; Sickmann, Albert; Chen, Yu-Ju; Jimenez, Connie R.; Zhou, Hu; Liu, Siqi; Larsen, Martin R.; Kislinger, Thomas; Chen, Zhinan; Parker, Benjamin L.; Cordwell, Stuart J.; Wollscheid, Bernd; Conrads, Thomas P.

Venue: N/A

Type: Publication

Abstract: AbstractCancer has no borders: Generation and analysis of molecular data across multiple centers worldwide is necessary to gain statistically significant clinical insights for the benefit of patients. Here we conceived and standardized a proteotype data generation and analysis workflow enabling distributed data generation and evaluated the quantitative data generated across laboratories of the international Cancer Moonshot consortium. Using harmonized mass spectrometry (MS) instrument platforms and standardized data acquisition procedures, we d... (read more)

Topics: Data science Medical physics Data mining

DOI: 10.1101/2020.03.12.988089

BIP! social metrics: 0 13
External links: Crossref OpenAIRE

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