BIP! Finder - Elevated regional cerebral blood flow in adults with 22q11.2 deletion syndrome

2022 • Elevated regional cerebral blood flow in adults with 22q11.2 deletion syndrome

Authors: Maurice Pasternak; Zahra Shirzadi; Henk J. M. M. Mutsaerts; Erik Boot; Nancy J. Butcher; Bradley J. MacIntosh; Tracy Heung; Anne S. Bassett; Mario Masellis

Venue: The World Journal of Biological Psychiatry

Type: Publication

Abstract: Recurrent chromosome 22q11.2 deletions cause 22q11 deletion syndrome (22q11DS), a multisystem disorder associated with high rates of schizophrenia. Neuroanatomical changes on brain MRI have been reported in relation to 22q11DS. However, to date no 22q11DS neuroimaging studies have examined cerebral blood flow (CBF). This exploratory case-control study seeks to identify differences in regional cerebral blood flow between 22q11DS subjects and controls, and their association with psychotic symptoms.This study of 23 adults used arterial spin labell... (read more)

Topics: Cardiology Internal medicine Neuroscience

DOI: 10.1080/15622975.2022.2093969

BIP! social metrics: 0 7
External links: Crossref OpenAIRE

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