BIP! Finder - A riboswitch-regulated antisense RNA in Listeria monocytogenes

2013 • A riboswitch-regulated antisense RNA in Listeria monocytogenes

Authors: J. R. Mellin; T. Tiensuu; C. Becavin; E. Gouin; J. Johansson; P. Cossart

Venue: Proceedings of the National Academy of Sciences

Type: Publication

Abstract: Riboswitches are ligand-binding elements located in 5′ untranslated regions of messenger RNAs, which regulate expression of downstream genes. In Listeria monocytogenes , a vitamin B 12 -binding (B 12 ) riboswitch was identified, not upstream of a gene but downstream, and antisense to the adjacent gene, pocR, suggesting it might regulate pocR in a nonclassical manner. In Salmonella enterica, PocR is a transcription factor that is activated by 1,2-propanediol, and subsequently activates expression of the pdu genes. The pdu genes mediate propane... (read more)

Impact:

3.2702758E-8 6.1514753E-9 103 39

/ Attention: 0 53

Topics: Cell biology Genetics

DOI: 10.1073/pnas.1304795110

External links: Crossref OpenAIRE

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