Single-molecule brightness analysis for the determination of anticancer drug interactions with DNA
Authors: Ying Zhou, Krzysztof Bielec, Pakorn Pasitsuparoad, Robert Hołyst
Venue: The Analyst
Abstract: We performed brightness analysis at a single molecular level of doxorubicin, daunorubicin, epirubicin, and idarubicin. The method was sensitive enough to confirm that the binding of drugs to the DNA occurs in two reactions.