2022 •
The War on hTG2: Warhead Optimization in Small Molecule Human Tissue Transglutaminase Inhibitors
Authors: Lavleen Mader, Sarah K.I. Watt, Harish R. Iyer, Linh Nguyen, Harpreet Kaur, Jeffrey W Keillor
Venue: RSC Medicinal Chemistry
Type: Article
Abstract: Human tissue transglutaminase (hTG2) is a multifunctional enzyme with protein cross-linking and G-protein activity, both of which have been implicated in the progression of diseases such as fibrosis and cancer...
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