Authors: Fagotti, Juliane, Targa, Adriano D. S., Rodrigues, Lais S., Noseda, Ana Carolina D., Dorieux, Flávia W. C., Scarante, Franciele F., Ilkiw, Jessica L., Louzada, Fernando M., Chowdhury, Namrata R., van der Veen, Daan R., Middleton, Benita, Pennings, Jeroen L. A., Swann, Jonathan R., Skene, Debra J., Lima, Marcelo M. S.
Venue: Scientific Reports
Type: Publication
Abstract: AbstractParkinson’s disease (PD) is a chronic disorder that presents a range of premotor signs, such as sleep disturbances and cognitive decline, which are key non-motor features of the disease. Increasing evidence of a possible association between sleep disruption and the neurodegenerative process suggests that sleep impairment could produce a detectable metabolic signature on the disease. In order to integrate neurocognitive and metabolic parameters, we performed untargeted and targeted metabolic profiling of the rotenone PD model in a chro...
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Topics: 
Bioinformatics
Neuroscience
Internal medicine
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