BIP! Finder - Variations in Jun and Fos protein expression and AP-1 activity in cycling, resting and stimulated fibroblasts

1997 • Variations in Jun and Fos protein expression and AP-1 activity in cycling, resting and stimulated fibroblasts

Authors: Dominique Lallemand, Giannis Spyrou, Moshe Yaniv, Curt M. Pfarr

Venue: Oncogene

Type: Publication

Abstract: We have analysed the different Jun and Fos proteins as NIH3T3 fibroblasts pass from exponential growth to quiescence and during the first 24 h after their re-entry into the cell cycle following serum stimulation. We show that these proteins can be divided into 3 subgroups based on their pattern of expression. The first contains c-Jun, Jun-D and Fra-2 which are expressed at high level in cycling cells and are only mildly induced by serum. The second contains Jun-B, c-Fos, Fos-B and deltaFos-B whose levels are low in cycling cells but increase st... (read more)

Topics: Cell biology Endocrinology

DOI: 10.1038/sj.onc.1200901

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External links: Crossref OpenAIRE

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