BIP! Finder - An environmentally relevant mixture of polychlorinated biphenyls (PCBs) and polybrominated diphenylethers (PBDEs) disrupts mitochondrial function, lipid metabolism and neurotransmission in the brain of exposed zebrafish and their unexposed F2 offspring

2021 • An environmentally relevant mixture of polychlorinated biphenyls (PCBs) and polybrominated diphenylethers (PBDEs) disrupts mitochondrial function, lipid metabolism and neurotransmission in the brain of exposed zebrafish and their unexposed F2 offspring

Authors: Mélanie Blanc; Sébastien Alfonso; Marie-Laure Bégout; Célia Barrachina; Tuulia Hyötyläinen; Steffen H. Keiter; Xavier Cousin

Venue: Science of The Total Environment

Type: Publication

Abstract: Polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) are persistent organic pollutants still present in aquatic environments despite their total or partial ban. Previously, we observed that an environmentally realistic mixture of these compounds affects energy balance, growth, and reproduction in exposed zebrafish (F0), and behavior in their unexposed offspring (F1-F4). In the present work, we performed lipidomic and transcriptomic analyses on brains of zebrafish (F0-F2) from exposed and control lineages to identify molec... (read more)

Impact:

2.984611E-8 3.4134024E-9 31 28

/ Attention: 0 77

Topics: Environmental chemistry

DOI: 10.1016/j.scitotenv.2020.142097

External links: Crossref OpenAIRE

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