BIP! Finder - The UK Standardisation of Breast Radiotherapy (START) trials of radiotherapy hypofractionation for treatment of early breast cancer: 10-year follow-up results of two randomised controlled trials

2013 • The UK Standardisation of Breast Radiotherapy (START) trials of radiotherapy hypofractionation for treatment of early breast cancer: 10-year follow-up results of two randomised controlled trials

Authors: Joanne S Haviland, J Roger Owen, John Dewar, R.K. Agrawal, Jane Barrett, Peter Barrett-Lee, H Jane Dobbs, Penelope Hopwood, Lawton Pa, Brian J Magee, J. Mills, Simmons S, M. Sydenham, K Venables, Judith M Bliss, John Yarnold

Venue: The Lancet Oncology

Type: Publication

Abstract: Summary Background 5-year results of the UK Standardisation of Breast Radiotherapy (START) trials suggested that lower total doses of radiotherapy delivered in fewer, larger doses (fractions) are at least as safe and effective as the historical standard regimen (50 Gy in 25 fractions) for women after primary surgery for early breast cancer. In this prespecified analysis, we report the 10-year follow-up of the START trials testing 13 fraction and 15 fraction regimens. Methods From 1999 to 2002, women with completely excised invasive breast cance... (read more)

Topics: Surgery Internal medicine

DOI: 10.1016/s1470-2045(13)70386-3

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External links: Crossref OpenAIRE

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