Authors: Martina Bocchetta, Marina Boccardi, Rossana Ganzola, Liana G. Apostolova, Gregory M. Preboske, Dominik Wolf, Clarissa Ferrari, Patrizio Pasqualetti, Nicolas Robitaille, Simon Duchesne, Clifford R. Jack, Giovanni B. Frisoni, George Bartzokis, Charles DeCarli, Leyla deToledo-Morrell, Andreas Fellgiebel, Michael J. Firbank, Lotte Gerritsen, Wouter J.P. Henneman, Ronald J. Killiany, Nikolai Malykhin, Jens C. Pruessner, Hilkka Soininen, Lei Wang

Venue: Alzheimer's & Dementia

Type: Publication

Abstract: Abstract Background A globally harmonized protocol (HarP) for manual hippocampal segmentation based on magnetic resonance has been recently developed by a task force from European Alzheimer's Disease Consortium (EADC) and Alzheimer's Disease Neuroimaging Initiative (ADNI). Our aim was to produce benchmark labels based on the HarP for manual segmentation. Methods Five experts of manual hippocampal segmentation underwent specific training on the HarP and segmented 40 right and left hippocampi from 10 ADNI subjects on both 1.5 T and 3 T scans. An ... (read more)

DOI: 10.1016/j.jalz.2013.12.019