BIP! Finder - Longitudinal effects of Nucleos(t)ide analogue therapy in chronic hepatitis B patients and the utility of non-invasive fibrosis markers during treatment: A single-center experience for up to 17 years

2019 • Longitudinal effects of Nucleos(t)ide analogue therapy in chronic hepatitis B patients and the utility of non-invasive fibrosis markers during treatment: A single-center experience for up to 17 years

Authors: Marc G. Ghany; Gil Ben-Yakov; Carly Broadwell; Varun Takyar; Devika Kapuria; T. Jake Liang; Pallavi Surana; Christopher Koh; Theo Heller; David E. Kleiner; Elizabeth C. Wright

Venue: Antiviral Research

Type: Publication

Abstract: Fibrosis regression has been associated with nucleoside analogue (NA) treatment in chronic hepatitis B (CHB) patients. Although non-invasive fibrosis markers have been evaluated in CHB, their utility for monitoring on-treatment histologic regression has not been evaluated.To characterize improvements in disease severity and the utility of non-invasive biomarkers in CHB NA treated patients.Histology, labs, AST-to-platelet ratio index, and Fibrosis-4 (Fib-4) from treatment-naïve CHB patients were evaluated at baseline and longitudinally. Relativ... (read more)

Topics: Internal medicine Gastroenterology Oncology

DOI: 10.1016/j.antiviral.2019.05.007

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External links: Crossref OpenAIRE

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