BIP! Finder - Are Physicochemical Properties Shaping the Allergenic Potency of Animal Allergens?

2021 • Are Physicochemical Properties Shaping the Allergenic Potency of Animal Allergens?

Authors: Costa, Joana; Villa, Caterina; Verhoeckx, Kitty; Cirkovic-Velickovic, Tanja; Schrama, Denise; Roncada, Paola; Rodrigues, Pedro M; Piras, Cristian; Martín-Pedraza, Laura; Monaci, Linda; Molina, Elena; Mazzucchelli, Gabriel; Mafra, Isabel; Lupi, Roberta; Lozano-Ojalvo, Daniel; Larré, Colette; Klueber, Julia; Gelencser, Eva; Bueno-Diaz, Cristina; Diaz-Perales, Araceli; Benedé, Sara; Bavaro, Simona Lucia; Kuehn, Annette; Hoffmann-Sommergruber, Karin; Holzhauser, Thomas

Venue: Clinical Reviews in Allergy & Immunology

Type: Publication

Abstract: Key determinants for the development of an allergic response to an otherwise 'harmless' food protein involve different factors like the predisposition of the individual, the timing, the dose, the route of exposure, the intrinsic properties of the allergen, the food matrix (e.g. lipids) and the allergen modification by food processing. Various physicochemical parameters can have an impact on the allergenicity of animal proteins. Following our previous review on how physicochemical parameters shape plant protein allergenicity, the same analysis w... (read more)

Impact: 9.769707E-8 5.6961276E-9 125 104 / Attention: 0 73

Topics: Computational biology Biotechnology Immunology

DOI: 10.1007/s12016-020-08826-1

External links: Crossref OpenAIRE

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