Abstract: Parkinson’s disease (PD) is a common neurodegenerative disorder for which genetic causes and susceptibility factors have been identified using linkage and association studies [1]. Many candidate genes have been investigated as risk factors for PD (www.pdgene.org) and several genome-wide association studies (GWAS) as well as three meta-analyses have been reported [5, 9, 10]. All GWAS indicate a strong association to several polymorphisms within the alpha-Synuclein (SNCA) gene, encoding a protein highly concentrated at presynaptic nerve termina...
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Topics: 
Genetics
Bioinformatics