Authors: Gil‐Moles, Maria, Türck, Sebastian, Basu, Uttara, Pettenuzzo, Andrea, Bhattacharya, Saurav, Rajan, Ananthu, Ma, Xiang, Büssing, Rolf, Wölker, Jessica, Burmeister, Hilke, Hoffmeister, Henrik, Schneeberg, Pia, Prause, Andre, Lippmann, Petra, Kusi‐Nimarko, Josephine, Hassell‐Hart, Storm, McGown, Andrew, Guest, Daniel, Lin, Yan, Notaro, Anna, Vinck, Robin, Karges, Johannes, Cariou, Kevin, Peng, Kun, Qin, Xue, Wang, Xing, Skiba, Joanna, Szczupak, Łukasz, Kowalski, Konrad, Schatzschneider, Ulrich, Hemmert, Catherine, Gornitzka, Heinz, Milaeva, Elena R., Nazarov, Alexey A., Gasser, Gilles, Spencer, John, Ronconi, Luca, Kortz, Cinatl, Jindrich, Bojkova, Denisa, Ott, Ingo
Venue: Chemistry – A European Journal
Type: Publication
Abstract: Abstract The global spread of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has called for an urgent need for dedicated antiviral therapeutics. Metal complexes are commonly underrepresented in compound libraries that are used for screening in drug discovery campaigns, however, there is growing evidence for their role in medicinal chemistry. Based on previous results, we have selected more than 100 structurally diverse metal complexes for profiling as inhibitors of two relevant SARS‐CoV‐2 replication mechanisms, namely...
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Topics: 
Virology
Combinatorial chemistry
Computational biology
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