Abstract: AbstractLaser Capture Microdissection (LCM) is a method that allows one to select and dissect well‐defined structures, specific cell subpopulations, or even single cells from different types of tissue for subsequent extraction of DNA, RNA, or proteins. Its precision allows the dissection of specific groups of cells, avoiding unwanted cells. However, despite its efficiency, several steps can affect the sample RNA integrity. RNA instability represents a challenge in the LCM method, and low RNA integrity can introduce biases, as different transc...
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Topics: 
Computational biology
Cell biology