Note: The reference list may be incomplete. This list contains all references that BIP software was able to retrieve.
Proteins regulating Ras and its relatives
Nature · 1993
Contributions of tumor and stromal matrix metalloproteinases to tumor progression, invasion and metastasis
Cancer and Metastasis Reviews · 1995
Activation of extracellular signal-regulated kinase, ERK2, by p21ras oncoprotein.
The EMBO Journal · 1992
Oncogenic Ras Downregulates Rac Activity, Which Leads to Increased Rho Activity and Epithelial–Mesenchymal Transition
Journal of Cell Biology · 2000
Altered Growth of Human Colon Cancer Cell Lines Disrupted at Activated Ki- ras
Science · 1993
Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor
Biochemical Journal · 1992
Comparison of ras activation during epidermal carcinogenesis in vitro and in vivo
Carcinogenesis · 1991
Rho-stimulated Contractility Contributes to the Fibroblastic Phenotype of Ras-transformed Epithelial Cells
Molecular Biology of the Cell · 1997
Hyperexpression of mitogen-activated protein kinase in human breast cancer.
Journal of Clinical Investigation · 1997
Variations in Jun and Fos protein expression and AP-1 activity in cycling, resting and stimulated fibroblasts
Oncogene · 1997
Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis
Nature · 1986
TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells.
Genes & Development · 1996
Evidence for the in vitro and in vivo interaction of Ras with protein kinase C zeta.
Journal of Biological Chemistry · 1994
Epithelial carcinogenesis in the mouse: correlating the genetics and the biology
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences · 1998
Inhibition of MAP Kinase Kinase Blocks the Differentiation of PC-12 Cells Induced by Nerve Growth Factor
Journal of Biological Chemistry · 1995
Transcriptional regulation of cell invasion
European Journal of Cancer · 2000
High levels of phosphorylated c-Jun, Fra-1, Fra-2 and ATF-2 proteins correlate with malignant phenotypes in the multistage mouse skin carcinogenesis model
Oncogene · 2000
Desensitization of Ras Activation by a Feedback Disassociation of the SOS-Grb2 Complex
Journal of Biological Chemistry · 1995
Direct Interaction between Ras and the Kinase Domain of Mitogen-activated Protein Kinase Kinase Kinase (MEKK1)
Journal of Biological Chemistry · 1995
ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK
Cell · 1992
Tumorigenicity of virus-transformed cells in nude mice is correlated specifically with anchorage independent growth in vitro.
Proceedings of the National Academy of Sciences · 1975
Annual Review of Biochemistry · 1987
Growth factors from murine sarcoma virus-transformed cells.
Proceedings of the National Academy of Sciences · 1978
Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo
Nature Medicine · 1999
Activated MEK Stimulates Expression of AP-1 Components Independently of Phosphatidylinositol 3-Kinase (PI3-Kinase) but Requires a PI3-Kinase Signal To Stimulate DNA Synthesis
Molecular and Cellular Biology · 1999
Transforming viruses directly reduce the cellular growth requirement for a platelet derived growth factor
Journal of Cellular Physiology · 1978
A Raf-independent Epidermal Growth Factor Receptor Autocrine Loop Is Necessary for Ras Transformation of Rat Intestinal Epithelial Cells
Journal of Biological Chemistry · 1997
Activation of an inducible c-FosER fusion protein causes loss of epithelial polarity and triggers epithelial-fibroblastoid cell conversion
Cell · 1992
A Role for the Ral Guanine Nucleotide Dissociation Stimulator in Mediating Ras-induced Transformation
Journal of Biological Chemistry · 1996
The Regulation of AP-1 Activity by Mitogen-activated Protein Kinases
Journal of Biological Chemistry · 1995
Mitogen-activated protein kinase/extracellular signal-regulated protein kinase activation by oncogenes, serum, and 12-O-tetradecanoylphorbol-13-acetate requires Raf and is necessary for transformation.
Journal of Biological Chemistry · 1994
Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation
Molecular and Cellular Biology · 1995
Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/beta-catenin complex in cells transformed with a temperature-sensitive v-SRC gene.
Journal of Cell Biology · 1993
EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor
Current Biology · 1994
Kirsten murine sarcoma virus transformed cell lines and a spontaneously transformed rat cell-line produce transforming factors
Journal of Cellular Physiology · 1980
PC12 cell neuronal differentiation is associated with prolonged p21ras activity and consequent prolonged ERK activity
Neuron · 1992
Raf induces TGFβ production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells
Genes & Development · 2000
Malignant transformation of early passage rodent cells by a single mutated human oncogene
Nature · 1984
Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation
Molecular and Cellular Biology · 1996
TGFβ signaling is necessary for carcinoma cell invasiveness and metastasis
Current Biology · 1998
Kinetic and biochemical correlation between sustained p44ERK1 (44 kDa extracellular signal-regulated kinase 1) activation and lysophosphatidic acid-stimulated DNA synthesis in Rat-1 cells
Biochemical Journal · 1996
Carcinogen-induced mutations in the mouse c-Ha-ras gene provide evidence of multiple pathways for tumor progression.
Proceedings of the National Academy of Sciences · 1990
Regulation of 92 kDa type IV collagenase expression by the jun aminoterminal kinase- and the extracellular signal-regulated kinase-dependent signaling cascades
Oncogene · 1997
Epithelial Cell Plasticity In Development And Tumor Progression.
Cancer and Metastasis Reviews · 1999
Phosphatidylinositol-3-OH kinase direct target of Ras
Nature · 1994
Role of matrix metalloproteinase-9 in progression of mouse skin carcinogenesis
Molecular Carcinogenesis · 2001
A synthetic inhibitor of the mitogen-activated protein kinase cascade.
Proceedings of the National Academy of Sciences · 1995
The conversion of mouse skin squamous cell carcinomas to spindle cell carcinomas is a recessive event
Journal of Cell Biology · 1993
Secreted or nonsecreted forms of acidic fibroblast growth factor produced by transfected epithelial cells influence cell morphology, motility, and invasive potential.
Proceedings of the National Academy of Sciences · 1991
Tyrosine phosphorylation regulates the adhesions of ras-transformed breast epithelia.
Journal of Cell Biology · 1995
Critical Role of Cellular ras Proteins in Proliferative Signal Transduction
Cold Spring Harbor Symposia on Quantitative Biology · 1988
Oncogene Activation in Chemical Carcinogenesis
Advances in Cancer Research · 1988
Autocrine Secretion and Malignant Transformation of Cells
New England Journal of Medicine · 1980
Genetic changes in skin tumor progression: Correlation between presence of a mutant ras gene and loss of heterozygosity on mouse chromosome 7
Cell · 1990