Note: The citation list may be incomplete. This list contains all citations that BIP software was able to retrieve.
Human exposure to synthetic endocrine disrupting chemicals (S-EDCs) is generally negligible as compared to natural compounds with higher or comparable endocrine activity: how to evaluate the risk of the S-EDCs?
Archives of Toxicology · 2020
Disposition of glycolic acid into rat and rabbit embryos in vitro
Reproductive Toxicology · 2014
Validation redefined
Toxicology in Vitro · 2018
Non-animal test methods for predicting skin sensitization potentials
Archives of Toxicology · 2012
Proposal for a Brazilian centre on alternative test methods
ALTEX · 2009
A State-of-the-Art Review on the Alternatives to Animal Testing for the Safety Assessment of Cosmetics
Cosmetics · 2022
Moving forward in carcinogenicity assessment: Report of an EURL ECVAM/ESTIV workshop
Toxicology in Vitro · 2017
The development and prevalidation of anin vitromutagenicity assay based on MutaMouse primary hepatocytes, Part I: Isolation, structural, genetic, and biochemical characterization
Environmental and Molecular Mutagenesis · 2018
Development of quantitative model of a local lymph node assay for evaluating skin sensitization potency applying machine learning CatBoost
Regulatory Toxicology and Pharmacology · 2021
Keratinocytes, Innate Immunity and Allergic Contact Dermatitis - Opportunities for the Development of In Vitro Assays to Predict the Sensitizing Potential of Chemicals
Contact Dermatitis · 2011
Editor's Highlight: Identification and Characterization of Teratogenic Chemicals Using Embryonic Stem Cells Isolated From a Wnt/β-Catenin-Reporter Transgenic Mouse Line
Toxicological Sciences · 2016
Animal testing and its alternatives – the most important omics is economics
ALTEX · 2018
Progress in gene expression profiling by the introduction of metagenes
Archives of Toxicology · 2012
Predicting chemically-induced skin reactions. Part I: QSAR models of skin sensitization and their application to identify potentially hazardous compounds
Toxicology and Applied Pharmacology · 2015
Design Principles of Concentration-Dependent Transcriptome Deviations in Drug-Exposed Differentiating Stem Cells
Chemical Research in Toxicology · 2014
Application of Gut Cell Models for Toxicological and Bioactivity Studies of Functional and Novel Foods
Foods · 2012
Importance of in vitro conditions for modeling the in vivo dose in humans by in vitro–in vivo extrapolation (IVIVE)
Archives of Toxicology · 2019
The Compromised Intestinal Barrier Induced by Mycotoxins
Toxins · 2020
Predictive Method Development: Challenges for Cosmetics and Genotoxicity as a Case Study
Methods and Principles in Medicinal Chemistry · 2014
The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods
Archives of Toxicology · 2020
A comprehensive review on recent advances in preparation, physicochemical characterization, and bioengineering applications of biopolymers
Polymer Bulletin · 2022
Perspectives and strategies of alternative methods used in the risk assessment of personal care products
Annales Pharmaceutiques Françaises · 2015
Overview on Current Status and Combination of Test Methods
Alternatives for Dermal Toxicity Testing · 2017
Overview on toxicity of nanoparticles, it's mechanism, models used in toxicity studies and disposal methods – A review
Biocatalysis and Agricultural Biotechnology · 2021
Alternative Methods for Developmental Toxicity Testing Using Mouse ESCs
Alternatives to Animal Testing · 2018
Modeling In Vitro Cell-Based Assays Experiments
Developments in Environmental Modelling · 2012
Genotoxicity testing: progress and prospects for the next decade
Expert Opinion on Drug Metabolism & Toxicology · 2017
Intelligent Testing Strategies
Risk Assessment of Chemicals · 2007
Development of an In Silico Profiler for Respiratory Sensitisation
Alternatives to Laboratory Animals · 2014
Pluripotent Stem Cells as Tools to Assess Developmental Toxicity: Diversity Instead of Consolidation
Handbook of Nanotoxicology, Nanomedicine and Stem Cell Use in Toxicology · 2014
Cosmetics Europe multi-laboratory pre-validation of the EpiOcular™ reconstituted human tissue test method for the prediction of eye irritation
Toxicology in Vitro · 2013
Predicting in silico the Direct-Peptide-Reactivity-Assay (DPRA) within the Allergic Contact Dermatitis framework
Toxicology Letters · 2017
Immunotoxicant Screening and Prioritization in the Twenty-first Century
Toxicologic Pathology · 2011
Toxicological evaluation of 3-(4-Chlorophenylselanyl)-1-methyl-1H-indole through the bovine oocyte in vitro maturation model
Toxicology in Vitro · 2020
OSIRIS, a quest for proof of principle for integrated testing strategies of chemicals for four human health endpoints
Regulatory Toxicology and Pharmacology · 2013
The use of biomarkers of toxicity for integrating in vitro hazard estimates into risk assessment for humans
ALTEX · 2012
“Watching the Detectives” report of the general assembly of the EU project DETECTIVE Brussels, 24–25 November 2015
Archives of Toxicology · 2016
Lung on a Chip for Drug Screening and Design
Current Pharmaceutical Design · 2019
Green Marketing
Sustainable Entrepreneurship and Investments in the Green Economy · 2017
Multi-dimensional computational pipeline for large-scale deep screening of compound effect assessment: an in silico case study on ageing-related compounds
npj Systems Biology and Applications · 2019
Allergic contact dermatitis: clinical aspects
Reviews on Environmental Health · 2014
An investigation into the formation of tebufenozide's toxic aromatic amine metabolites in human in vitro hepatic microsomes
Pesticide Biochemistry and Physiology · 2016
Advancing the predictivity of skin sensitization by applying a novel HMOX1 reporter system
Archives of Toxicology · 2018
Challenges in working towards an internal threshold of toxicological concern (iTTC) for use in the safety assessment of cosmetics: Discussions from the Cosmetics Europe iTTC Working Group workshop
Regulatory Toxicology and Pharmacology · 2019
Guidance for submission for food additive evaluations
EFSA Journal · 2012
Advanced In Vitro Lung Models for Drug and Toxicity Screening: The Promising Role of Induced Pluripotent Stem Cells
Advanced Biology · 2021
Concluding Remarks
Replacing Animal Models · 2012
Considering new methodologies in strategies for safety assessment of foods and food ingredients
Food and Chemical Toxicology · 2016
The development and prevalidation of an in vitro mutagenicity assay based on MutaMouse primary hepatocytes, Part II: Assay performance for the identification of mutagenic chemicals
Environmental and Molecular Mutagenesis · 2019
A Critical Review of Adverse Outcome Pathway-Based Concepts and Tools for Integrating Information from Nonanimal Testing Methods: The Case of Skin Sensitization
Applied In Vitro Toxicology · 2017
Strategies for the optimisation of in vivo experiments in accordance with the 3Rs philosophy
Regulatory Toxicology and Pharmacology · 2012
Biosensors to Monitor Cell Activity in 3D Hydrogel-Based Tissue Models
Sensors · 2022
Analysis of real-time mixture cytotoxicity data following repeated exposure using BK/TD models
Toxicology and Applied Pharmacology · 2016
A new computer-controlled air–liquid interface cultivation system for the generation of differentiated cell cultures of the airway epithelium
Experimental and Toxicologic Pathology · 2016
Geraniol and linalool anticandidal activity, genotoxic potential and embryotoxic effect on zebrafish
Future Microbiology · 2018
The Use of Integrated and Intelligent Testing Strategies in the Prediction of Toxic Hazard and in Risk Assessment
Advances in Experimental Medicine and Biology · 2012
<i>In silico</i> risk assessment for skin sensitization using artificial neural network analysis
The Journal of Toxicological Sciences · 2015
From in vitro hepatic metabolic studies towards human health risk assessment: Two case studies of diuron and carbosulfan
Pesticide Biochemistry and Physiology · 2013
Use of physiologically based kinetic modeling-facilitated reverse dosimetry of in vitro toxicity data for prediction of in vivo developmental toxicity of tebuconazole in rats
Toxicology Letters · 2017
Extracellular matrix: The ideal natural fibrous nanocomposite products
Applications of Nanocomposite Materials in Orthopedics · 2019
Validation of the GARD™skin Assay for Assessment of Chemical Skin Sensitizers: Ring Trial Results of Predictive Performance and Reproducibility
Toxicological Sciences · 2019
Bayesian integrated testing strategy to assess skin sensitization potency: from theory to practice
Journal of Applied Toxicology · 2013
A Balanced Risk–Benefit Analysis to Determine Human Risks Associated with Pyrrolizidine Alkaloids (PA)—The Case of Tea and Herbal Infusions
Nutrients · 2017
Animal-Free Chemical Safety Assessment
Frontiers in Pharmacology · 2016
Safety Evaluation of Cosmetic Ingredients: In Vitro Opportunities for the Identification of Contact Allergens
Cosmetics · 2014
In Vitro–In Vivo Carcinogenicity
In vitro Environmental Toxicology - Concepts, Application and Assessment · 2016
Final Publication of the “Regulations on the Supervision and Administration of Cosmetics” and New Prospectives of Cosmetic Science in China
Cosmetics · 2020
PopGen: A virtual human population generator
Toxicology · 2014
Developmental neurotoxicity: the case of perfluoroalkylated compounds
Archives of Toxicology · 2012
Analysis of publically available skin sensitization data from REACH registrations 2008-2014
ALTEX · 2016
The Potential Use of Three-Dimensional Cellular Multilayers as a Blood Vessel Model
Nanomedicine and Nanotoxicology · 2014
Occludin gene expression as an early in vitro sign for mild eye irritation assessment
Toxicology in Vitro · 2010
Polysaccharide-Based Bioink Formulation for 3D Bioprinting of an In Vitro Model of the Human Dermis
Nanomaterials · 2020
The cytoprotective and the dark side of Nrf2
Archives of Toxicology · 2013
Alternatives for skin sensitisation: Hazard identification and potency categorisation: Report from an EPAA/CEFIC LRI/Cosmetics Europe cross sector workshop, ECHA Helsinki, April 23rd and 24th 2015
Regulatory Toxicology and Pharmacology · 2015
Report from the EPAA workshop: In vitro ADME in safety testing used by EPAA industry sectors
Toxicology in Vitro · 2011
Cross matching observations on toxicological and clinical data for the assessment of tolerability and safety of Ginkgo biloba leaf extract
Toxicology · 2015
Biokinetics in repeated-dosing in vitro drug toxicity studies
Toxicology in Vitro · 2015
In Vitro Design of Nanoparticles Using an Artificial 3D-Blood Vessel Wall Model for Atherosclerosis Treatment
ACS Symposium Series · 2017
Safety assessment of cosmetic products, with emphasis on the ocular area: regulatory aspects and validation processes
Brazilian Journal of Pharmaceutical Sciences · 2014
Potential Applications Of Human Artificial Skin And Electronic Skin (e-skin): A Review
Bioinspired Biomimetic And Nanobiomaterials · 2017
Interpreting in vitro developmental toxicity test battery results: The consideration of toxicokinetics
Reproductive Toxicology · 2015
Further experience with the local lymph node assay using standard radioactive and nonradioactive cell count measurements
Journal of Applied Toxicology · 2012
Expert opinions on the acceptance of alternative methods in food safety evaluations: Formulating recommendations to increase acceptance of non-animal methods for kinetics
Regulatory Toxicology and Pharmacology · 2018
Structure–Potency Relationships for Epoxides in Allergic Contact Dermatitis
Chemical Research in Toxicology · 2017
A microelectric cell sensing technique for in vitro assessment of ocular irritation
Toxicology in Vitro · 2021
Predictive models for nanotoxicology: in vitro, in vivo, and computational models
Handbook of Nanotechnology Applications · 2021
Reconstructed Skin Micronucleus Assay (RSMN)
Alternatives for Dermal Toxicity Testing · 2017
Perspectives in toxicologic pathology: quantification of bile canalicular networks
Archives of Toxicology · 2014
Mechanism Profiling of Hepatotoxicity Caused by Oxidative Stress Using Antioxidant Response Element Reporter Gene Assay Models and Big Data.
Environmental Health Perspectives · 2015
Profiling of drugs and environmental chemicals for functional impairment of neural crest migration in a novel stem cell-based test battery
Archives of Toxicology · 2014
Probabilistic hazard assessment for skin sensitization potency by dose-response modeling using feature elimination instead of quantitative structure-activity relationships
Journal of Applied Toxicology · 2015
3D Bioprinting · 2019
Estimation of the chemical-induced eye injury using a Weight-of-Evidence (WoE) battery of 21 artificial neural network (ANN) c-QSAR models (QSAR-21): Part II: Corrosion potential
Regulatory Toxicology and Pharmacology · 2015
An expert consortium review of the EC-commissioned report “Alternative (Non-Animal) Methods for Cosmetics Testing: Current Status and Future Prospects – 2010”
ALTEX · 2011
Extrapolating In Vitro Results to Predict Human Toxicity
Methods in Pharmacology and Toxicology · 2014
Screening of chemicals for human bioaccumulative potential with a physiologically based toxicokinetic model
Archives of Toxicology · 2011
Integrated testing strategies for safety assessments
ALTEX · 2013
In Vitro–In Vivo Extrapolation
Encyclopedia of Toxicology · 2014
Progress in the Development, Validation and Regulatory Acceptance of In Vitro Methods for Toxicity Testing
Reference Module in Chemistry, Molecular Sciences and Chemical Engineering · 2013
Proteomic allergen–peptide/protein interaction assay for the identification of human skin sensitizers
Toxicology in Vitro · 2013
Reproductive Toxicity
Methods in Pharmacology and Toxicology · 2014
ChemSkin Reference Chemical Database for the Development of an In Vitro Skin Irritation Test
Toxics · 2021
In chemico, in vitro and in vivo comparison of the skin sensitizing potential of eight unsaturated and one saturated lipid compounds
Regulatory Toxicology and Pharmacology · 2017
Systemic Nanotoxicity and Its Assessment in Animal Models
Nanopharmaceuticals: Principles and Applications Vol. 3 · 2020
Alternative Approaches for Carcinogenicity and Reproductive Toxicity
The History of Alternative Test Methods in Toxicology · 2019
Experimental verification, and domain definition, of structural alerts for protein binding: epoxides, lactones, nitroso, nitros, aldehydes and ketones
SAR and QSAR in Environmental Research · 2013
Integrative Strategy of Testing Systems for Identification of Endocrine Disruptors Inducing Metabolic Disorders—An Introduction to the OBERON Project
International Journal of Molecular Sciences · 2020
Safety Assessment of Cosmetic Ingredients
Cosmetic Science and Technology · 2017
The Pros and Cons of the In-silico Pharmaco-toxicology in Drug Discovery and Development
International Journal of Pharmacology · 2013
Regulatory toxicology in the twenty-first century: challenges, perspectives and possible solutions
Archives of Toxicology · 2015
Alternative Animal and Non-Animal Models for Drug Discovery and Development: Bonus or Burden?
Pharmaceutical Research · 2016
The ECVAM International Validation Study on In Vitro Tests for Acute Skin Irritation: Selection of Test Chemicals
Alternatives to Laboratory Animals · 2007
Alternative animal toxicity testing and biomarkers
Biomarkers in Toxicology · 2014
Skin Penetration
Cosmetic Science and Technology · 2017
Artificial Intelligence-Based Toxicity Prediction of Environmental Chemicals: Future Directions for Chemical Management Applications
Environmental Science & Technology · 2022
Establishing a systematic framework to characterise in vitro methods for human hepatic metabolic clearance
Toxicology in Vitro · 2018
Moving from rats to cellular omics in regulatory toxicology: great challenge toward sustainability or “up-shit-creek without a paddle”?
Archives of Toxicology · 2015
Alternative Animal Toxicity Testing and Biomarkers
Biomarkers in Toxicology · 2019
Relative embryotoxic potency of p-substituted phenols in the embryonic stem cell test (EST) and comparison to their toxic potency in vivo and in the whole embryo culture (WEC) assay
Toxicology Letters · 2012
Integrated Testing Strategies for Toxicity Employing New and Existing Technologies
Alternatives to Laboratory Animals · 2011
A human skin model to evaluate the protective effect of compounds against UVA damage
International Journal of Cosmetic Science · 2019
Application of in silico and in vitro methods in the development of adverse outcome pathway constructs in wildlife
Philosophical Transactions of the Royal Society B: Biological Sciences · 2014
Is the replacement strategy, as it exists today in the EU for cosmetics, the way forward ?
Archives of Toxicology · 2011
The usefulness of toxicogenomics for predicting acute skin irritation on in vitro reconstructed human epidermis
Toxicology · 2007
Review of current and “omics” methods for assessing the toxicity (genotoxicity, teratogenicity and nephrotoxicity) of herbal medicines and mushrooms
Journal of Ethnopharmacology · 2012
A critical appraisal of the process of regulatory implementation of novelin vivoandin vitromethods for chemical hazard and risk assessment
Critical Reviews in Toxicology · 2014
International ring trial of the epidermal equivalent sensitizer potency assay: reproducibility and predictive capacity
ALTEX · 2014
Evaluation of in vitro assays for the assessment of the skin sensitization hazard of functional polysiloxanes and silanes
Regulatory Toxicology and Pharmacology · 2017
Computational pharmacokinetics at a crossroads
In Silico Pharmacology · 2013
ECVAM prevalidation study on in vitro cell transformation assays: General outline and conclusions of the study
Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2012
Approaches and considerations for the assessment of immunotoxicity for environmental chemicals: A workshop summary
Regulatory Toxicology and Pharmacology · 2014
Contact dermatitis: from pathomechanisms to immunotoxicology
Experimental Dermatology · 2012
Categorization of Chemicals According to Their Relative Human Skin Sensitizing Potency
Dermatitis · 2014
Integrating in vitro chemical transplacental passage into a generic PBK model: A QIVIVE approach
Toxicology · 2022
Effects of Polychlorinated Biphenyls 28, 30 and 118 on Bovine SpermatozoaIn Vitro
Reproduction in Domestic Animals · 2014
3S - Systematic, systemic, and systems biology and toxicology
ALTEX · 2018
Ecological values
Ethics and Business · 2021
Gene expressions changes in bronchial epithelial cells: Markers for respiratory sensitizers and exploration of the NRF2 pathway
Toxicology in Vitro · 2014
Reprint of PopGen: A virtual human population generator
Toxicology · 2015
Allergic Contact Dermatitis
Applied Dermatotoxicology · 2014
A strategy for safety assessment of chemicals with data gaps for developmental and/or reproductive toxicity
Regulatory Toxicology and Pharmacology · 2015
A review on genotoxicity in connection to infertility and cancer
Chemico-Biological Interactions · 2021
In vitro genotoxicity testing–Can the performance be enhanced?
Food and Chemical Toxicology · 2017
Integrated Testing Strategies for Skin Sensitization Hazard and Potency Assessment—State of the Art and Challenges
Cosmetics · 2016
Towards AOP application – Implementation of an integrated approach to testing and assessment (IATA) into a pipeline tool for skin sensitization
Regulatory Toxicology and Pharmacology · 2014
An international validation study of the IL-2 Luc assay for evaluating the potential immunotoxic effects of chemicals on T cells and a proposal for reference data for immunotoxic chemicals
Toxicology in Vitro · 2020
Chemicals: cosmetics and other consumer products
Information Resources in Toxicology · 2020
AbstractsIn Vitro Toxicology Society Annual Meeting10–11 November 2014AstraZeneca, Alderley ParkMacclesfield, United Kingdom
Applied In Vitro Toxicology · 2015
Wind of Change Challenges Toxicological Regulators
Environmental Health Perspectives · 2012
Nanostructured-lipid carriers-Chitosan hydrogel beads carrier system for loading of resveratrol: A new method of topical application
Journal of Biomaterials Applications · 2022
Scientific Opinion on the hazard assessment of endocrine disruptors: Scientific criteria for identification of endocrine disruptors and appropriateness of existing test methods for assessing effects mediated by these substances on human health and the environment
EFSA Journal · 2013
Fluorescence-based recombination assay for sensitive and specific detection of genotoxic carcinogens in human cells
Archives of Toxicology · 2014
Alternative in vitro models for safety and toxicity evaluation of nutraceuticals
Nutraceuticals · 2021
The importance of mathematical modelling in chemical risk assessment and the associated quantification of uncertainty
Computational Toxicology · 2019
The identification of nuclear receptors associated with hepatic steatosis to develop and extend adverse outcome pathways
Critical Reviews in Toxicology · 2015
Human exposure to synthetic endocrine disrupting chemicals (S-EDCs) is generally negligible as compared to natural compounds with higher or comparable endocrine activity. How to evaluate the risk of the S-EDCs?
Journal of Toxicology and Environmental Health, Part A · 2020
State of the art in non-animal approaches for skin sensitization testing: from individual test methods towards testing strategies
Archives of Toxicology · 2016
Chemical carcinogen safety testing: OECD expert group international consensus on the development of an integrated approach for the testing and assessment of chemical non-genotoxic carcinogens
Archives of Toxicology · 2020
Functional Fragments of AIMP1-Derived Peptide (AdP) and Optimized Hydrosol for Their Topical Deposition by Box-Behnken Design
Molecules · 2019
Need for Harmonized Strategies and Improved Assessment of Carcinogenic and Genotoxic Potencies of Chemical Substances
Journal of Translational Toxicology · 2014
What happens in the skin? Integrating skin permeation kinetics into studies of developmental and reproductive toxicity following topical exposure
Reproductive Toxicology · 2015
Non-animal models of epithelial barriers (skin, intestine and lung) in research, industrial applications and regulatory toxicology
ALTEX · 2015
Biotransformation in vitro: An essential consideration in the quantitative in vitro-to-in vivo extrapolation (QIVIVE) of toxicity data
Toxicology · 2015
Paradigm shift in safety assessment using new approach methods: The EU-ToxRisk strategy
Current Opinion in Toxicology · 2019
Contact hypersensitivity: Integrated approaches to testing and assessment
Current Opinion in Toxicology · 2017
Applying non-animal strategies for assessing skin sensitisation report from an EPAA/cefic-LRI/IFRA Europe cross sector workshop, ECHA helsinki, February 7th and 8th 2019
Regulatory Toxicology and Pharmacology · 2019
PBPK Modeling to Simulate the Fate of Compounds in Living Organisms
Methods in Molecular Biology · 2022
Implementation of toxicokinetics in toxicity studies – Toxicokinetics of 4-methylanisole and its metabolites in juvenile and adult rats
Regulatory Toxicology and Pharmacology · 2015
Utilization of Peptide Reactivity Assays for the Prediction of Skin Sensitization
Alternatives for Dermal Toxicity Testing · 2017
A comparison of the embryonic stem cell test and whole embryo culture assay combined with the BeWo placental passage model for predicting the embryotoxicity of azoles
Toxicology Letters · 2018
A framework for application of quantitative property-property relationships (QPPRs) in physiologically based pharmacokinetic (PBPK) models for high-throughput prediction of internal dose of inhaled organic chemicals
Chemosphere · 2019
Toxicity of Nanoparticles on the Reproductive System in Animal Models: A Review
Frontiers in Pharmacology · 2017
Preventing false-negatives in the in vitro skin sensitization testing of acid anhydrides using interleukin-8 release assays
Toxicology in Vitro · 2017
Internal threshold of toxicological concern values: enabling route-to-route extrapolation
Archives of Toxicology · 2014
A category approach to predicting the developmental (neuro) toxicity of organotin compounds: The value of the zebrafish (Danio rerio) embryotoxicity test (ZET)
Reproductive Toxicology · 2013
Integrated Approaches to Testing and Assessment
Basic & Clinical Pharmacology & Toxicology · 2018
Assessment of an in vitro transport model using BeWo b30 cells to predict placental transfer of compounds
Archives of Toxicology · 2013
Method for detecting the reactivity of chemicals towards peptides as an alternative test method for assessing skin sensitization potential
Toxicology Letters · 2014
Can currently available non-animal methods detect pre and pro-haptens relevant for skin sensitization?
Regulatory Toxicology and Pharmacology · 2016
EURL ECVAM strategy to avoid and reduce animal use in genotoxicity testing
N/A · 2013
Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach
Archives of Toxicology · 2012
Development and validation of regression-based QSAR models for quantification of contributions of molecular fragments to skin sensitization potency of diverse organic chemicals
SAR and QSAR in Environmental Research · 2013
Non-animal assessment of skin sensitization hazard: Is an integrated testing strategy needed, and if so what should be integrated?
Journal of Applied Toxicology · 2017
ESNATS Conference — The use of Human Embryonic Stem Cells for Novel Toxicity Testing Approaches
Alternatives to Laboratory Animals · 2014
In Silico Toxicology – Non-Testing Methods
Frontiers in Pharmacology · 2011
Use of ‘omics to elucidate mechanism of action and integration of ‘omics in a systems biology concept
Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2012
Alternative methods for regulatory toxicology – a state-of-the-art review
N/A · 2014
Current EU regulatory requirements for the assessment of chemicals and cosmetic products: challenges and opportunities for introducing new approach methodologies
Archives of Toxicology · 2021
The use of non-animal alternatives in the safety evaluations of cosmetics ingredients by the Scientific Committee on Consumer Safety (SCCS)
Regulatory Toxicology and Pharmacology · 2015
An epidermal equivalent assay for identification and ranking potency of contact sensitizers
Toxicology and Applied Pharmacology · 2013
Alternative methods to safety studies in experimental animals: role in the risk assessment of chemicals under the new European Chemicals Legislation (REACH)
Archives of Toxicology · 2008
Comparison and validation of an in vitro skin sensitization strategy using a data set of 33 chemical references
Toxicology in Vitro · 2017
ECVAM Technical Report on the Status of Alternative Methods for Cosmetics Testing (2008-2009)
N/A · 2010
Bacterial cellulose based facial mask with antioxidant property and high moisturizing capacity
Cellulose · 2021
In vitro and In vivo Toxicity Assessment of Metallic Nanoparticulate Systems for Skin Targeting
Current Nanotoxicity and Prevention · 2021
Optimised testing strategies for skin sensitization – The LLNA and beyond
Regulatory Toxicology and Pharmacology · 2012
Applying the skin sensitisation adverse outcome pathway (AOP) to quantitative risk assessment
Toxicology in Vitro · 2014
Young Researchers — The Ethical Challenge
Alternatives to Laboratory Animals · 2015
Biomarkers of Toxicity in Human Placenta
Biomarkers in Toxicology · 2019
Anchoring molecular mechanisms to the adverse outcome pathway for skin sensitization: Analysis of existing data
Critical Reviews in Toxicology · 2014
Utilizing Organoid and Air-Liquid Interface Models as a Screening Method in the Development of New Host Defense Peptides
Frontiers in Cellular and Infection Microbiology · 2020
Cutaneous Allergies
Molecular and Integrative Toxicology · 2012
Risk Assessment of residual monomer migrating from acrylic polymers and causing Allergic Contact Dermatitis during normal handling and use
Regulatory Toxicology and Pharmacology · 2014
Species-specific models in toxicology: in vitro epithelial barriers
Environmental Toxicology and Pharmacology · 2019
Introduction to Toxicogenomics-Based Cellular Models
Toxicogenomics-Based Cellular Models · 2014
Extracellular matrix: A dynamic microenvironment for stem cell niche
Biochimica et Biophysica Acta (BBA) - General Subjects · 2014
Concurrent evaluation of general, immune, and genetic toxicity endpoints as part of an integrated testing strategy
Environmental and Molecular Mutagenesis · 2014
Potential of coculture in vitro models to study inflammatory and sensitizing effects of particles on the lung
Toxicology in Vitro · 2011
Bayesian integrated testing strategy (ITS) for skin sensitization potency assessment: a decision support system for quantitative weight of evidence and adaptive testing strategy
Archives of Toxicology · 2015
Real-time monitoring of oxygen uptake in hepatic bioreactor shows CYP450-independent mitochondrial toxicity of acetaminophen and amiodarone
Archives of Toxicology · 2015
Toxicology: a discipline in need of academic anchoring—the point of view of the German Society of Toxicology
Archives of Toxicology · 2015
EURL ECVAM Recommendation on the Direct Peptide Reactivity Assay (DPRA) for Skin Sensitisation Testing
N/A · 2013
Stem Cells for Drug Screening
Recent Advances in Stem Cells · 2016
Reassessing the two-year rodent carcinogenicity bioassay: A review of the applicability to human risk and current perspectives
Regulatory Toxicology and Pharmacology · 2014
Unlocking the potential of in silico chemical safety assessment – A report on a cross-sector symposium on current opportunities and future challenges
Computational Toxicology · 2019
Correlating in vitro data to in vivo findings for risk assessment
ALTEX · 2014
EURL ECVAM Strategy for Replacement of Animal Testing for Skin Sensitisation Hazard Identification and Classification
N/A · 2013
Bewertung des sensibilisierenden Potenzials von Stoffen in Kosmetika und Bedarfsgegenständen
Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz · 2012
Screening of repeated dose toxicity data present in SCC(NF)P/SCCS safety evaluations of cosmetic ingredients
Archives of Toxicology · 2011
Systems biology modeling of omics data: effect of cyclosporine a on the Nrf2 pathway in human renal cells
BMC Systems Biology · 2014
ECVAM and New Technologies for Toxicity Testing
Advances in Experimental Medicine and Biology · 2012
Xenobiotic metabolizing enzyme activities in cells used for testing skin sensitization in vitro
Archives of Toxicology · 2013
The virtual cell based assay: Current status and future perspectives
Toxicology in Vitro · 2017