@article{Madden_2012,
title={Strategies for the optimisation of in vivo experiments in accordance with the 3Rs philosophy},
volume={63},
ISSN={0273-2300},
url={http://dx.doi.org/10.1016/j.yrtph.2012.03.010},
DOI={10.1016/j.yrtph.2012.03.010},
number={1},
journal={Regulatory Toxicology and Pharmacology},
publisher={Elsevier BV},
author={Madden,
Judith C. and Hewitt,
Mark and Przybylak,
Katarzyna and Vandebriel,
Rob J. and Piersma,
Aldert H. and Cronin,
Mark T.D.},
year={2012},
month=jun,
pages={140–154} }