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2021 • Caution When Comparing the Impact of Corticosteroids in COVID-19.

Authors: Marco Confalonieri, Francesco Salton, Paola Confalonieri, Bram Rochwerg, G. Umberto Meduri

Abstract: Meta-analyses have the advantage of providing a summary effect estimate when there are a number of methodologically homogenous studies that examine the same intervention in the same study populations. Fortyfive days after the publication of the Recovery trial, a meta-analysis of eight randomized trials (7,184 participants) was published, and a corresponding WHO guideline panel subsequently recommended systemic corticosteroids in patients with severe and critical COVID-19 (strong recommendation, based on moderate certainty evidence).

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Caution When Comparing the Impact of Corticosteroids in COVID-19

Marco Confalonieri, Francesco Salton, Paola Confalonieri, Bram Rochwerg, G. Umberto Meduri

Chest · 2021

Intensive care medicine |

Open Access

Article