2011 •
Improving Outcomes in Sepsis and Septic Shock: Getting it Right the First Time
Authors:
Duane J. Funk, Shravan Kethireddy, Anand Kumar, Anand Kumar
Abstract:
Infections among critically ill patients have convincingly been shown to directly increase mortality, prolong hospital length of stays, and increase healthcare costs (Chastre and Fagon 2002; Rello et al. 2002). In the past the general approach to antimicrobial therapy of infection involved an escalation strategy wherein patients were started on the narrowest reasonable antimicrobial regimen expected to cover a majority of common pathogens. In addition to mild and moderately ill patients, this strategy was also applied to the critically ill at h (...)
Infections among critically ill patients have convincingly been shown to directly increase mortality, prolong hospital length of stays, and increase healthcare costs (Chastre and Fagon 2002; Rello et al. 2002). In the past the general approach to antimicrobial therapy of infection involved an escalation strategy wherein patients were started on the narrowest reasonable antimicrobial regimen expected to cover a majority of common pathogens. In addition to mild and moderately ill patients, this strategy was also applied to the critically ill at high risk of death. (Read More)
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