2020 •
Data underlying the publication: "Lateral induction limits the impact of cell connectivity on Notch signaling in arterial walls"
Authors: Ristori, Tommaso, Stassen, O. M. J. A. (Oscar), Sahlgren, C. M. (Cecilia), Loerakker, S. (Sandra)
Venue: 4TU.ResearchData
Type: Dataset
Abstract: This study extends a previous 1D agent-based model for Notch signaling in arteries to a 2D formulation. This allows investigation of the effects of cell connectivity on the dynamics of arterial Notch signaling and VSMC phenotypes. Notch signaling for VSMCs with 2-6 neighbouring cells was analyzed. Computational results of the 1D and 2D formulations were also compared.
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