Authors: Junya L, Singulani, Reginaldo S, Pedroso, Arthur B, Ribeiro, Heloiza D, Nicolella, Karoline S, Freitas, Jacqueline L, Damasceno, Tatiana M, Vieira, Antônio Em, Crotti, Denise C, Tavares, Carlos Hg, Martins, Maria Js, Mendes-Giannini, Regina H, Pires
Venue: Future Microbiology
Type: Publication
Abstract: Aim: Geraniol and linalool are major constituents of the essential oils of medicinal plants. Materials & methods: Antifungal activity of geraniol and linalool were evaluated against five Candida species. The genotoxicity of these compounds was evaluated by the cytokinesis-block micronucleus test, and the embryotoxic assays use zebrafish model. Results: Geraniol and linalool inhibited Candida growth, but geraniol was more effective. The geraniol at concentration of 800 μg/ml and the linalool at concentration of 125 μg/ml significantly incr...
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Topics: 
Toxicology
Computational biology
Genetics
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