Abstract: Virtual screening (VS) coupled with structural biology is a significantly important approach to increase the number and enhance the success of projects in lead identification stage of drug discovery process. Recent advances and future directions in estrogen therapy have resulted in great demand for identifying the potential estrogen receptor (ER) modulators with more activity and selectivity.This review presents the current state of the art in VS and structure-activity relationship of ER modulators in recent discovery, and discusses the strengt...
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Topics: 
Computational biology
Neuroscience
Bioinformatics