Authors: Bas J, Blaauboer, Kim, Boekelheide, Harvey J, Clewell, Mardas, Daneshian, Milou M L, Dingemans, Alan M, Goldberg, Marjoke, Heneweer, Joanna, Jaworska, Nynke I, Kramer, Marcel, Leist, Hasso, Seibert, Emanuela, Testai, Rob J, Vandebriel, James D, Yager, Joanne, Zurlo
Venue: ALTEX
Type: Publication
Abstract: The role that in vitro systems can play in toxicological risk assessment is determined by the appropriateness of the chosen methods, with respect to the way in which in vitro data can be extrapolated to the in vivo situation. This report presents the results of a workshop aimed at better defining the use of in vitro-derived biomarkers of toxicity (BoT) and determining the place these data can have in human risk assessment. As a result, a conceptual framework is presented for the incorporation of in vitro-derived toxicity data into the risk asse...
(read more)
Topics: 
Risk analysis (engineering)
Biochemical engineering
Loading (it may take a couple of seconds)...
Loading (it may take a couple of seconds)...