Abstract: ABSTRACT Background and aim: Laser capture microdissection is used to obtain pure cell populations, thus allowing the study of molecular pathological mechanisms from specific cell populations, yet RNA from tissues fixed in formalin (the most common fixative for analysis of gene expression) is usually degraded during microdissection and RNA extraction. In this study we investigate the best fixative for use in the preparation of human tissues for laser capture microdissection, and for the preservation of RNA molecules and histomorphologic structu...
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Topics: 
Molecular biology