Abstract: In study of the brain, oxygenation changes in the cerebral cortex are of great interest, since the concentrations of oxyhaemoglobin and deoxyhaemoglobin change due to coupling of hemodynamics to cortical neural activity. In order to noninvasively monitor oxygenation in the cerebral cortex by nearinfrared spectroscopy (NIRS), light should penetrate into brain tissue to a depth of approximately 1-2 cm.Many studies show that by increasing the source-detector distance, illuminating light penetrates deeper into brain tissue. Using tissue-mimicking p...
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Topics: 
Biomedical engineering
Optics
Nuclear magnetic resonance