Authors: Håvard, Aanes, Cecilia L, Winata, Chi Ho, Lin, Jieqi P, Chen, Kandhadayar G, Srinivasan, Serene G P, Lee, Adrian Y M, Lim, Hajira Shreen, Hajan, Philippe, Collas, Guillaume, Bourque, Zhiyuan, Gong, Vladimir, Korzh, Peter, Aleström, Sinnakaruppan, Mathavan
Venue: Genome Research
Type: Publication
Abstract: Maternally deposited mRNAs direct early development before the initiation of zygotic transcription during mid-blastula transition (MBT). To study mechanisms regulating this developmental event in zebrafish, we applied mRNA deep sequencing technology and generated comprehensive information and valuable resources on transcriptome dynamics during early embryonic (egg to early gastrulation) stages. Genome-wide transcriptome analysis documented at least 8000 maternal genes and identified the earliest cohort of zygotic transcripts. We determined expr...
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Topics: 
Genetics
Computational biology
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