Authors: David A, Basketter, Nathalie, Alépée, Takao, Ashikaga, João, Barroso, Nicola, Gilmour, Carsten, Goebel, Jalila, Hibatallah, Sebastian, Hoffmann, Petra, Kern, Silvia, Martinozzi-Teissier, Gavin, Maxwell, Kerstin, Reisinger, Hitoshi, Sakaguchi, Andreas, Schepky, Magalie, Tailhardat, Marie, Templier
Venue: Dermatitis
Type: Publication
Abstract: Although adoption of skin sensitization in vivo assays for hazard identification is likely to be successful in the next few years, this does not replace their use in potency prediction. Notably, measurement of potency of skin sensitizers in the local lymph node assay has been important. However, this local lymph node assay potency measure has not been formally assessed against a range of substances of known human sensitizing potential, because the latter is lacking. Accordingly, criteria for human data have been established that characterize 6 ...
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Topics: 
Pharmacology
Toxicology
Computational biology
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